product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human ARPP19 protein
catalog :
ATGP2449
quantity :
20 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human ARPP19 protein
Domain :
1-112aa
Catalog number (SKU) :
ATGP2449
NCBI :
NP_006619
Description :
cAMP-regulated phosphoprotein 19, also known as ARPP19, is protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-62 during mitosis, specifically interacts with PPP2R2D (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase. This protein may indirectly enhance GAP-43 expression. Recombinant human ARPP19 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
cAMP-regulated phosphoprotein 19, cAMP-regulated phosphoprotein 19, ARPP-16, ARPP-19, ARPP16, ENSAL
Concentration :
0.5mg/ml (determined by BCA assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Gharbi-Ayachi A., et al. (2010) Science. 330:1673-1677;; Choudhary C., et al. (2009) Science. 325:834-840
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Signal Transduction
Molecular Weight :
14.7 kDa (135aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MGSSHHHHHH SSGLVPRGSH MGSMSAEVPE AASAEEQKEM EDKVTSPEKA EEAKLKARYP HLGQKPGGSD FLRKRLQKGQ KYFDSGDYNM AKAKMKNKQL PTAAPDKTEV TGDHIPTPQD LPQRKPSLVA SKLAG
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
P56211
Internal Search Terms :
ARPP19, cAMP-regulated phosphoprotein 19, cAMP-regulated phosphoprotein 19, ARPP-16, ARPP-19, ARPP16, ENSAL,ATGP2449-10ug,ATGP2449-20ug,ATGP2449-50ug,ATGP2449-100ug,ATGP2449-250ug,ATGP2449-500ug,ATGP2449-1mg,ATGP2449-10,ATGP2449-20,ATGP2449-50,ATGP2449-100,ATGP2449-250,ATGP2449-500,ATGP2449-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.