product summary
Loading...
company name :
NKMAX
product type :
protein
product name :
Recombinant human BEND6 protein
catalog :
ATGP2441
quantity :
20 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human BEND6 protein
Domain :
1-279aa
Catalog number (SKU) :
ATGP2441
NCBI :
NP_689944
Description :
BEND6, as known as BEN domain-containing protein 6, is a neural BEN-solo factor that shares many functional attributes with Drosophila Insensitive, a co-repressor for the Drosophila CSL factor. This protein binds the mammalian CSL protein CBF1 and antagonizes Notch-dependent target activation. In addition, its association with Notch- and CBF1-regulated enhancers is promoted by CBF1 and antagonized by activated Notch. In utero electroporation experiments showed that ectopic BEND6 inhibited Notch-mediated self-renewal of neocortical neural stem cells and promoted neurogenesis. Recombinant human BEND6 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Alternative Names :
BEN domain-containing protein 6, bA203B9.1, C6orf65
Concentration :
1mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.1M NaCl
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Dai Q. et al. (2013) Development. 140:1892-1902;; Chu J. et al. (2004) J Biol Chem. 279:12337-12345.
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Other
Molecular Weight :
33.6 kDa (302aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MGSSHHHHHH SSGLVPRGSH MGSMQKIVQT DEITNTQAFR KGKRKRTETM DSENANSDMD KGQRDPYSGN AFLPGESSSE DEEPLAELSK EELCAKIKSL KEKLTNTRKE NSRLRQSLVM LQVLPQAVTQ FEELVGMAEA LLKGGGTMST SASTLWRATN NSSPDSFAST CSNSNSNSSS PVSLKPEEEH QTDEKQFQIE KWQIARCNKS KPQKFINDLM QVLYTNEYMA THSLTGAKSS TSRDKAVKPA MNQNEVQEII GVTKQLFPNT DDVSIRRMIG QKLNNCTKKP NLSKNLNSQD IK
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
Q5SZJ8
Internal Search Terms :
BEND6, BEN domain-containing protein 6, bA203B9.1, C6orf65,ATGP2441-10ug,ATGP2441-20ug,ATGP2441-50ug,ATGP2441-100ug,ATGP2441-250ug,ATGP2441-500ug,ATGP2441-1mg,ATGP2441-10,ATGP2441-20,ATGP2441-50,ATGP2441-100,ATGP2441-250,ATGP2441-500,ATGP2441-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.