product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human Sirtuin 5/SIRT5 protein
catalog :
ATGP2434
quantity :
20 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human Sirtuin 5/SIRT5 protein
Domain :
34-310aa
Catalog number (SKU) :
ATGP2434
NCBI :
NP_036373.1
Description :
SIRT5 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class III of the sirtuin family. Alternative splicing of this gene results in multiple transcript variants Recombinant human SIRT5 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
NAD-dependent protein deacylase sirtuin-5 mitochondrial, Regulatory protein SIR2 homolog 5, SIR2-like protein 5, SIR2L5
Concentration :
0.5mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol, 1mM DTT
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Zhou,Y., et al. (2012) J. Biol. Chem. 287 (34), 28307-28314;; Fischer,F., et al. (2012) PLoS ONE 7 (9), E45098
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Metabolism
Molecular Weight :
32.5 kDa (300aa) confirmed by MALDI-TOF
Amino Acid Sequence :
ARPSSSM ADFRKFFAKA KHIVIISGAG VSAESGVPTF RGAGGYWRKW QAQDLATPLA FAHNPSRVWE FYHYRREVMG SKEPNAGHRA IAECETRLGK QGRRVVVITQ NIDELHRKAG TKNLLEIHGS LFKTRCTSCG VVAENYKSPI CPALSGKGAP EPGTQDASIP VEKLPRCEEA GCGGLLRPHV VWFGENLDPA ILEEVDRELA HCDLCLVVGT SSVVYPAAMF APQVAARGVP VAEFNTETTP ATNRFRFHFQ GPCGTTLPEA LACHENETVS
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
Q9NXA8
Internal Search Terms :
Sirtuin5, SIRT5, sirtuin 5, SIR2L5,ATGP2434-10ug,ATGP2434-20ug,ATGP2434-50ug,ATGP2434-100ug,ATGP2434-250ug,ATGP2434-500ug,ATGP2434-1mg,ATGP2434-10,ATGP2434-20,ATGP2434-50,ATGP2434-100,ATGP2434-250,ATGP2434-500,ATGP2434-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.