product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human TRIAP1 protein
catalog :
ATGP2431
quantity :
20 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human TRIAP1 protein
Domain :
1-76aa
Catalog number (SKU) :
ATGP2431
NCBI :
NP_057483
Description :
TP53-regulated inhibitor of apoptosis 1, also known as TRIAP1, contains a p53-binding site within its second exon and the reduction of expression by small interfering RNA enhanced apoptosis, whereas overexpression protected cells from apoptosis caused by DNA damage. TRIAP1 is induced significantly when cells have a low level of genotoxic stresses, but not when DNA damage is severe. TRIAP1 can modulate apoptotic pathways through interaction with Hsp70 that probably inhibits activity of apoptosis protease activating factor-1. Recombinant human TRIAP1, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
TP53-regulated inhibitor of apoptosis 1, HSPC132, MDM35, P53CSV, WF-1
Concentration :
1mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 20% glycerol, 1mM DTT
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Park WR., et al. (2005) Cancer Res. 65(4): 1197-206.;; Staib F., et al. (2005) Cancer Res. 65(22): 10255-64.
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Apoptosis
Molecular Weight :
11.2 kDa (99aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MGSSHHHHHH SSGLVPRGSH MGSMNSVGEA CTDMKREYDQ CFNRWFAEKF LKGDSSGDPC TDLFKRYQQC VQKAIKEKEI PIEGLEFMGH GKEKPENSS
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
O43715
Internal Search Terms :
TRIAP1, TP53-regulated inhibitor of apoptosis 1, HSPC132, MDM35, P53CSV, WF-1,ATGP2431-10ug,ATGP2431-20ug,ATGP2431-50ug,ATGP2431-100ug,ATGP2431-250ug,ATGP2431-500ug,ATGP2431-1mg,ATGP2431-10,ATGP2431-20,ATGP2431-50,ATGP2431-100,ATGP2431-250,ATGP2431-500,ATGP2431-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.