protein

Recombinant human EVI-1 protein

ATGP2426

4 ug

80 USD

Recombinant human EVI-1 protein

1-169aa

ATGP2426

NP_004982.1

MDS1 is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene. Recombinant human MDS1 protein, fused to His-tag at N-terminus, was expressed in E. coli

MDS1 and EVI1 complex locus, myelodysplasia syndrome 1, ecotropic viral integration site 1, MDS1, EVI1, PRDM3, MDS1-EVI1

0.25mg/ml (determined by Bradford assay)

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing , 10% glycerol, 0.4M urea

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Fears S., et al. (1996) Proc. Natl. Acad. Sci. u.S.A. 93:1642-1647.

> 85% by SDS-PAGE

SDS-PAGE, Denatured

Human

Epigenomics (Transcription & Translation)

21.1 kDa (192aa)

MGSSHHHHHH SSGLVPRGSH MGSMRSKGRA RKLATNNECV YGNYPEIPLE EMPDADGVAS TPSLNIQEPC SPATSSEAFT PKEGSPYKAP IYIPDDIPIP AEFELRESNM PGAGLGIWTK RKIEVGEKFG PYVGEQRSNL KDPSYGWEVH LPRSRRVSVH SWLYLGKRSS DVGIAFSQAD VYMPGLQCAF LS

His-Tag

E.coli

Recombinant Protein

Q03112

PRDM3, Myelodysplasia syndrome protein 1, Myelodysplasia syndrome 1, MRI, Modulator of retrovirus infection homolog, MDS1-EVI1, MDS1 EVI1, MDS1 and EVI1 complex locus, MDS1, EVI1, Ecotropic viral integration site 1, Cell cycle regulator of non-homologous end joining, Cell cycle regulator of non homologous end joining, C7orf49, ATGP2426-10ug, ATGP2426-20ug, ATGP2426-50ug, ATGP2426-100ug, ATGP2426-250ug, ATGP2426-500ug, ATGP2426-1mg, ATGP2426-010, ATGP2426-020, ATGP2426-050, ATGP2426-100, ATGP2426-250, ATGP2426-500, ATGP2426-01M