Recombinant human Vav-1 protein | NKMAX ATGP2424 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Vav-1 protein

catalog :

ATGP2424

quantity :

4 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Vav-1 protein

Domain :

189-565aa

Catalog number (SKU) :

ATGP2424

NCBI :

NP_005419

Description :

Proto-oncogene vav isoform 1, also known as VAV1, is a member of the VAV gene family. The VAV1 proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. In addition, VAV1 contains an SH2 domain, which could indicate its role as a substrate for tyrosine kinases. Expression of VAV1 is limited exclusively to cells of hematopoietic origin, including those of the erythroid, lymphoid and myeloid lineages. Recombinant human VAV1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Proto-oncogene vav isoform 1, Proto-oncogene vav isoform 1, VAV, Proto-oncogene vav, vav 1 guanine nucleotide exchange factor, vav 1 oncogene

Concentration :

0.25mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 30% glycerol, 2mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Bustelo X R., et al. (1992) Nature. 356:68-71.;; Katzav S., et al. (1989) EMBO J. 8:2283-2290.;;

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cancer

Molecular Weight :

46.8 kDa (400aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MTEYDKR CCCLREIQQT EEKYTDTLGS IQQHFLKPLQ RFLKPQDIEI IFINIEDLLR VHTHFLKEMK EALGTPGAAN LYQVFIKYKE RFLVYGRYCS QVESASKHLD RVAAAREDVQ MKLEECSQRA NNGRFTLRDL LMVPMQRVLK YHLLLQELVK HTQEAMEKEN LRLALDAMRD LAQCVNEVKR DNETLRQITN FQLSIENLDQ SLAHYGRPKI DGELKITSVE RRSKMDRYAF LLDKALLICK RRGDSYDLKD FVNLHSFQVR DDSSGDRDNK KWSHMFLLIE DQGAQGYELF FKTRELKKKW MEQFEMAISN IYPENATANG HDFQMFSFEE TTSCKACQML LRGTFYQGYR CHRCRASAHK ECLGRVPPCG

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P15498

Internal Search Terms :

Vav1, Proto-oncogene vav isoform 1, Proto-oncogene vav isoform 1, VAV, Proto-oncogene vav, vav 1 guanine nucleotide exchange factor, vav 1 oncogene,ATGP2424-10ug,ATGP2424-20ug,ATGP2424-50ug,ATGP2424-100ug,ATGP2424-250ug,ATGP2424-500ug,ATGP2424-1mg,ATGP2424-10,ATGP2424-20,ATGP2424-50,ATGP2424-100,ATGP2424-250,ATGP2424-500,ATGP2424-1

more info or order :

NKMAX product webpage