Recombinant human RNF34 protein | NKMAX ATGP2419 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human RNF34 protein

catalog :

ATGP2419

quantity :

20 ug

price :

105 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human RNF34 protein

Domain :

1-373aa

Catalog number (SKU) :

ATGP2419

NCBI :

NP_919247

Description :

RNF34contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. This protein also targets p53 and phospho-p53 for degradation. Alternatively splicing results in multiple transcript variants encoding distinct isoforms. Recombinant human RNF34 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Alternative Names :

E3 ubiquitin-protein ligase RNF34 isoform 1, CARP-1, CARP1, Caspase regulator CARP1, Caspases-8 and-10-associated RING finger protein 1, E3 ubiquitin-protein ligase, ring finger protein 34, FLJ21786, RIF, RIFF, E3 ubiquitin protein ligase RNF34 isoform 1

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.1M NaCl, 1mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Wei P. et al. (2012) Mol Cell Biol. 32:266-275.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Ubiquitination

Molecular Weight :

44.2 kDa (396aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MGSMRKAGAT SMWASCCGLL NEVMGTGAVR GQQSAFAGAT GPFRFTPNPE FSTYPPAATE GPNIVCKACG LSFSVFRKKH VCCDCKKDFC SVCSVLQENL RRCSTCHLLQ ETAFQRPQLM RLKVKDLRQY LILRNIPIDT CREKEDLVDL VLCHHGLGSE DDMDTSSLNS SRSQTSSFFT RSFFSNYTAP SATMSSFQGE LMDGDQTSRS GVPAQVQSEI TSANTEDDDD DDDEDDDDEE ENAEDRNPGL SKERVRASLS DLSSLDDVEG MSVRQLKEIL ARNFVNYSGC CEKWELVEKV NRLYKENEEN QKSYGERLQL QDEEDDSLCR ICMDAVIDCV LLECGHMVTC TKCGKRMSEC PICRQYVVRA VHVFKS

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q969K3

Internal Search Terms :

RNF34, E3 ubiquitin-protein ligase RNF34 isoform 1, CARP-1, CARP1, Caspase regulator CARP1, Caspases-8 and-10-associated RING finger protein 1, E3 ubiquitin-protein ligase, ring finger protein 34, FLJ21786, RIF, RIFF, E3 ubiquitin protein ligase RNF34 isoform 1,ATGP2419-10ug,ATGP2419-20ug,ATGP2419-50ug,ATGP2419-100ug,ATGP2419-250ug,ATGP2419-500ug,ATGP2419-1mg,ATGP2419-10,ATGP2419-20,ATGP2419-50,ATGP2419-100,ATGP2419-250,ATGP2419-500,ATGP2419-1

more info or order :

NKMAX product webpage