Recombinant mouse RAPSN protein | NKMAX ATGP2405 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant mouse RAPSN protein

catalog :

ATGP2405

quantity :

20 ug

price :

105 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant mouse RAPSN protein

Domain :

1-412aa

Catalog number (SKU) :

ATGP2405

NCBI :

NP_033049

Description :

43 kDa receptor-associated protein of the synapse, also known as RAPSN, is expressed in the postsynaptic membrane of skeletal muscle. RAPSN is required for the clustering of nicotinic acetylcholine receptors (nAChR). It self-associates through at least two of its seven tetra-tricopeptide repeats (TPRs). RAPSN interacts with the large intracellular domain of the nAChR a subunit through the hydrophobic surface of the coiled-coil domain. This protein modifies trafficking of AChR within the cell. Overexpression inhibits agrin-induced AChR clustering pathway. Recombinant human RAPSN protein, fused to His-tag at N-terminus, was expressed in E. coli.

Alternative Names :

43 kDa receptor-associated protein of the synapse, 43kDa, Nraps, Raps, rapsyn

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Maimone M M., et al. (1999) Mol Cell Neurosci. 14:340-354.;; Han H., et al. (1999) J Neurocytol. 28:763-775;;

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE,Denatured

Antigen Species :

Mouse

Gene Category :

Neuroscience

Molecular Weight :

48.8 kDa (435aa)

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MGSMGQDQTK QQIEKGLQLY QSNQTEKALQ VWMKVLEKGS DLVGRFRVLG CLVTAHSEMG RYKEMLKFAV VQIDTARGLE DADFLLESYL NLARSNEKLC EFHKTISYCK TCLGLPGTRA GAQLGGQVSL SMGNAFLGLS LFQKALESFE KALRYAHNND DTMLECRVCC SLGSFYAQVK DYEKALFFPC KAAELVNDYG KGWSLKYRAM SQYHMAVAYR LLGHLGSAME CCEESMKIAL QHGDRPLQAL CLLCFADIHR SRGDLETAFP RYDSAMSIMT EIGNRLGQVH VLLGVAKCWM ARKVQDKALD AIEKAQDLAE EVGNKLSQLK LHCLSESIYR SKGLQRELRT HVVRFHECVE ETELYCGLCG ESIGERNSRL QALPCSHIFH LRCLQNNGTR SCPNCRRSSM KPGFV

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P12672

Internal Search Terms :

RAPSN, 43 kDa receptor-associated protein of the synapse, 43kDa, Nraps, Raps, rapsyn,ATGP2405-10ug,ATGP2405-20ug,ATGP2405-50ug,ATGP2405-100ug,ATGP2405-250ug,ATGP2405-500ug,ATGP2405-1mg,ATGP2405-10,ATGP2405-20,ATGP2405-50,ATGP2405-100,ATGP2405-250,ATGP2405-500,ATGP2405-1

more info or order :

NKMAX product webpage