Recombinant human MAP1/MOAP1 protein | NKMAX ATGP2404 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human MAP1/MOAP1 protein

catalog :

ATGP2404

quantity :

20 ug

price :

105 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human MAP1/MOAP1 protein

Domain :

1-351aa

Catalog number (SKU) :

ATGP2404

NCBI :

NP_071434

Description :

Modulator of apoptosis 1, also known as MOAP1, belongs to the PNMA family and contains one BH3-like domain and one RASSF1-binding domain. It is required for death receptor-dependent apoptosis. MOAP1 homodimerizes and associates with the proapoptotic Bax and the prosurvival Bcl-2 and Bcl-X (L) of the Bcl-2 family in vitro and in vivo in mammalian cells. These data suggest that MOAP1 mediates apoptosis through a mechanism that involves binding to Bax. Recombinant human MOAP1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Alternative Names :

Modulator of apoptosis 1, MAP-1, PNMA4, Paraneoplastic antigen Ma4

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Baksh S., et al. (2005) Mol Cell. 18:637-650.;; Tan K O., et al. (2001) J Biol Chem. 276:2802-2807.;;

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE, Denatured

Antigen Species :

Human

Gene Category :

Apoptosis

Molecular Weight :

41.9 kDa (374aa)

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MGSMTLRLLE DWCRGMDMNP RKALLIAGIS QSCSVAEIEE ALQAGLAPLG EYRLLGRMFR RDENRKVALV GLTAETSHAL VPKEIPGKGG IWRVIFKPPD PDNTFLSRLN EFLAGEGMTV GELSRALGHE NGSLDPEQGM IPEMWAPMLA QALEALQPAL QCLKYKKLRV FSGRESPEPG EEEFGRWMFH TTQMIKAWQV PDVEKRRRLL ESLRGPALDV IRVLKINNPL ITVDECLQAL EEVFGVTDNP RELQVKYLTT YQKDEEKLSA YVLRLEPLLQ KLVQRGAIER DAVNQARLDQ VIAGAVHKTI RRELNLPEDG PAPGFLQLLV LIKDYEAAEE EEALLQAILE GNFT

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q96BY2

Internal Search Terms :

MOAP1, Modulator of apoptosis 1, MAP-1, PNMA4,ATGP2404-10ug,ATGP2404-20ug,ATGP2404-50ug,ATGP2404-100ug,ATGP2404-250ug,ATGP2404-500ug,ATGP2404-1mg,ATGP2404-10,ATGP2404-20,ATGP2404-50,ATGP2404-100,ATGP2404-250,ATGP2404-500,ATGP2404-1

more info or order :

NKMAX product webpage