Recombinant human eIF-3 beta/EIF3I protein | NKMAX ATGP2393 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human eIF-3 beta/EIF3I protein

catalog :

ATGP2393

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human eIF-3 beta/EIF3I protein

Domain :

1-325aa

Catalog number (SKU) :

ATGP2393

NCBI :

NP_003748

Description :

EIF3I is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2: GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AuG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. Recombinant human EIF3I protein, fused to His-tag at N-terminus, was expressed in E. coli.

Alternative Names :

C3orf68, eIF3-beta, eIF-3-beta, eIF3i, eIF3-p36, EIF3S2, Eukaryotic translation initiation factor 3 subunit 2, Eukaryotic translation initiation factor 3 subunit 2 beta 36kDa, Eukaryotic translation initiation factor 3 subunit I, PRO2242, TGF-beta receptor-interacting protein 1, TRIP1, TRIP-1

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Proshkin,S.A., et al. (2011) Biochemistry Mosc. 76 (8), 976-980;; Perez,R.E., et al. (2011) Am. J. Physiol. Lung Cell Mol. Physiol. 300 (5), L799-L807;;

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE, Denatured

Antigen Species :

Human

Gene Category :

Epigenomics (Transcription & Translation)

Molecular Weight :

38.9 kDa (348aa)

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MGSMKPILLQ GHERSITQIK YNREGDLLFT VAKDPIVNVW YSVNGERLGT YMGHTGAVWC VDADWDTKHV LTGSADNSCR LWDCETGKQL ALLKTNSAVR TCGFDFGGNI IMFSTDKQMG YQCFVSFFDL RDPSQIDNNE PYMKIPCNDS KITSAVWGPL GECIIAGHES GELNQYSAKS GEVLVNVKEH SRQINDIQLS RDMTMFVTAS KDNTAKLFDS TTLEHQKTFR TERPVNSAAL SPNYDHVVLG GGQEAMDVTT TSTRIGKFEA RFFHLAFEEE FGRVKGHFGP INSVAFHPDG KSYSSGGEDG YVRIHYFDPQ YFEFEFEA

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q13347

Internal Search Terms :

EIF3I, eukaryotic translation initiation factor 3 subunit I, C3orf68,ATGP2393-10ug,ATGP2393-20ug,ATGP2393-50ug,ATGP2393-100ug,ATGP2393-250ug,ATGP2393-500ug,ATGP2393-1mg,ATGP2393-10,ATGP2393-20,ATGP2393-50,ATGP2393-100,ATGP2393-250,ATGP2393-500,ATGP2393-1

more info or order :

NKMAX product webpage