Recombinant human QKI protein | NKMAX ATGP2377 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human QKI protein

catalog :

ATGP2377

quantity :

10 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human QKI protein

Domain :

1-341aa

Catalog number (SKU) :

ATGP2377

NCBI :

NP_006766

Description :

Protein quaking isoform HQK-5, also known as QKI, is an RNA-binding protein that regulates pre-mRNA splicing, export of mRNAs from the nucleus, protein translation, and mRNA stability. It is involved in myelinization and oligodendrocyte differentiation, and it may play a role in schizophrenia. Defects or deletions in the QKI are associated with astrocytic tumors and may be involved in the pathogenesis of schizophrenia. Recombinant human QKI protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Protein quaking isoform HQK-5, Hqk, hqkI, QK, QK1, QK3

Concentration :

0.25mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 2mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Hardy R J., et al. (1996) J Neurosci. 16: 7941-7949.;; Ebersole T A., et al. (1996) Nat Genet. 12: 260-265.;;

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Epigenomics (Transcription & Translation)

Molecular Weight :

40.1 kDa (364aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MGSMVGEMET KEKPKPTPDY LMQLMNDKKL MSSLPNFCGI FNHLERLLDE EISRVRKDMY NDTLNGSTEK RSAELPDAVG PIVQLQEKLY VPVKEYPDFN FVGRILGPRG LTAKQLEAET GCKIMVRGKG SMRDKKKEEQ NRGKPNWEHL NEDLHVLITV EDAQNRAEIK LKRAVEEVKK LLVPAAEGED SLKKMQLMEL AILNGTYRDA NIKSPALAFS LAATAQAAPR IITGPAPVLP PAALRTPTPA GPTIMPLIRQ IQTAVMPNGT PHPTAAIVPP GPEAGLIYTP YEYPYTLAPA TSILEYPIEP SGVLGAVATK VRRHDMRVHP YQRIVTADRA ATGN

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q96PU8

Internal Search Terms :

QKI, Protein quaking isoform HQK-5, Hqk, hqkI, QK, QK1, QK3,ATGP2377-10ug,ATGP2377-20ug,ATGP2377-50ug,ATGP2377-100ug,ATGP2377-250ug,ATGP2377-500ug,ATGP2377-1mg,ATGP2377-10,ATGP2377-20,ATGP2377-50,ATGP2377-100,ATGP2377-250,ATGP2377-500,ATGP2377-1

more info or order :

NKMAX product webpage