Recombinant human UBC3B/UBE2R2 protein | NKMAX ATGP2374 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human UBC3B/UBE2R2 protein

catalog :

ATGP2374

quantity :

10 ug

price :

105 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human UBC3B/UBE2R2 protein

Domain :

1-238aa

Catalog number (SKU) :

ATGP2374

NCBI :

NP_060281

Description :

UBE2R2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This protein is a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation. Recombinant human UBE2R2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Ubiquitin-conjugating enzyme E2 R2, E2 ubiquitin-conjugating enzyme R2, Ubiquitin carrier protein R2, Ubiquitin-conjugating enzyme E2-CDC34B, Ubiquitin-protein ligase R2, CDC34B, UBC3B

Concentration :

0.25mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Yoshida,T., et al. (2010) Int. J. Mol. Med. 25 (4), 649-656;; Oguri,M., et al. (2006) Am. J. Hypertens. 23 (1), 70-77;;

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Epigenomics (Transcription & Translation)

Molecular Weight :

29.6 kDa (261aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

Amino Acid Sequence :

MAQQQMT SSQKALMLEL KSLQEEPVEG FRITLVDESD LYNWEVAIFG PPNTLYEGGY FKAHIKFPID YPYSPPTFRF LTKMWHPNIY ENGDVCISIL HPPVDDPQSG ELPSERWNPT QNVRTILLSV ISLLNEPNTF SPANVDASVM FRKWRDSKGK DKEYAEIIRK QVSATKAEAE KDGVKVPTTL AEYCIKTKVP SNDNSSDLLY DDLYDDDIDD EDEEEEDADC YDDDDSGNEE S

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q712K3

Internal Search Terms :

CDC34B, E2 CDC34B, E2 ubiquitin conjugating enzyme R2, E2 ubiquitin-conjugating enzyme R2, E2CDC34B, E2-CDC34B, UBC3B, UBE2R2, Ubiquitin carrier protein R2, Ubiquitin conjugating enzyme E2 R2, Ubiquitin conjugating enzyme E2-CDC34B, Ubiquitin protein ligase R2, Ubiquitin-conjugating enzyme E2 R2, Ubiquitin-conjugating enzyme E2-CDC34B, Ubiquitin-protein ligase R2, Ubiquitin conjugating enzyme E2 CDC34B, Ubiquitin-conjugating enzyme E2 CDC34B, ATGP2374-10ug, ATGP2374-20ug, ATGP2374-50ug, ATGP2374-100ug, ATGP2374-250ug, ATGP2374-500ug, ATGP2374-1mg, ATGP2374-010, ATGP2374-020, ATGP2374-050, ATGP2374-100, ATGP2374-250, ATGP2374-500, ATGP2374-01M

more info or order :

NKMAX product webpage