Recombinant human TFPI protein | NKMAX ATGP2333 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human TFPI protein

catalog :

ATGP2333

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human TFPI protein

Domain :

29-304aa

Catalog number (SKU) :

ATGP2333

NCBI :

NP_006278

Description :

TFPI is a protease inhibitor that regulates the tissue factor (TF) -dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The protein inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. TFPI is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been confirmed. Recombinant human TFPI protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

tissue factor pathway inhibitor, EPI, LACI, TFI, TFPI1

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M uREA, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Prabhakar,P., et al. (2012) Thromb. Res. 130 (4), 687-689 ;; Alioglu,B., et al. (2012) J Clin Res Pediatr Endocrinol 4 (3), 146-150;;

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE, Denatured

Antigen Species :

Human

Gene Category :

Cardiovascular

Molecular Weight :

34.3 kDa (299aa)

Amino Acid Sequence :

DSEEDEE HTIITDTELP PLKLMHSFCA FKADDGPCKA IMKRFFFNIF TRQCEEFIYG GCEGNQNRFE SLEECKKMCT RDNANRIIKT TLQQEKPDFC FLEEDPGICR GYITRYFYNN QTKQCERFKY GGCLGNMNNF ETLEECKNIC EDGPNGFQVD NYGTQLNAVN NSLTPQSTKV PSLFEFHGPS WCLTPADRGL CRANENRFYY NSVIGKCRPF KYSGCGGNEN NFTSKQECLR ACKKGFIQRI SKGGLIKTKR KRKKQRVKIA YEEIFVKNM

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P10646

Internal Search Terms :

TFPI, tissue factor pathway inhibitor, EPI, LACI, TFI, TFPI1,ATGP2333-10ug,ATGP2333-20ug,ATGP2333-50ug,ATGP2333-100ug,ATGP2333-250ug,ATGP2333-500ug,ATGP2333-1mg,ATGP2333-10,ATGP2333-20,ATGP2333-50,ATGP2333-100,ATGP2333-250,ATGP2333-500,ATGP2333-1

more info or order :

NKMAX product webpage