Recombinant human DUSP26 protein | NKMAX ATGP2324 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human DUSP26 protein

catalog :

ATGP2324

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human DUSP26 protein

Domain :

1-211aa

Catalog number (SKU) :

ATGP2324

NCBI :

NP_076930

Description :

DuSP26 inactivates MAPK1 and MAPK3 which leads to dephosphorylation of heat shock factor protein 4 and a reduction in its DNA-binding activity. This protein inhibits MAP kinase p38 by dephosphorylating it and inhibits p38-mediated apoptosis in anaplastic thyroid cancer cells. DuSP26 can also induce activation of MAP kinase p38 and c-Jun N-terminal kinase (JNK). Recombinant human DuSP26 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Alternative Names :

Dual specificity protein phosphatase 26, Dual specificity phosphatase SKRP3, Low-molecular-mass dual-specificity phosphatase 4, DSP-4, LDP-4, Mitogen-activated protein kinase phosphatase 8, MAP kinase phosphatase 8, MKP-8, Novel amplified gene in thyroid anaplastic cancer, Neuroendocrine-associated phosphatase, DUSP24, LDP4, MKP8, NATA1, SKRP3, NEAP

Concentration :

0.25mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M urea

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Vasudevan S.A. et al. (2005). Biochem. Biophys. Res. Commun. 330:511-518;; Yu W., et al. (2007). Oncogene 26:1178-1187;;

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE, Denatured

Antigen Species :

Human

Gene Category :

Signal Transduction

Molecular Weight :

26.3 kDa (234aa)

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MGSMCPGNWL WASMTFMARF SRSSSRSPVR TRGTLEEMPT VQHPFLNVFE LERLLYTGKT ACNHADEVWP GLYLGDQDMA NNRRELRRLG ITHVLNASHS RWRGTPEAYE GLGIRYLGVE AHDSPAFDMS IHFQTAADFI HRALSQPGGK ILVHCAVGVS RSATLVLAYL MLYHHLTLVE AIKKVKDHRG IIPNRGFLRQ LLALDRRLRQ GLEA

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q9BV47

Internal Search Terms :

DuSP26, Dual specificity protein phosphatase 26, Dual specificity protein phosphatase 26, Dual specificity phosphatase 26 (putative), DuSP24, LDP-4, MKP8, NATA1, SKRP3,ATGP2324-10ug,ATGP2324-20ug,ATGP2324-50ug,ATGP2324-100ug,ATGP2324-250ug,ATGP2324-500ug,ATGP2324-1mg,ATGP2324-10,ATGP2324-20,ATGP2324-50,ATGP2324-100,ATGP2324-250,ATGP2324-500,ATGP2324-1

more info or order :

NKMAX product webpage