product summary
Loading...
company name :
NKMAX
product type :
protein
product name :
Recombinant human KIAA0101/PCLAF protein
catalog :
ATGP2304
quantity :
10 ug
price :
106 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human KIAA0101/PCLAF protein
Domain :
1-111aa
Catalog number (SKU) :
ATGP2304
NCBI :
NP_055551.1
Description :
KIAA0101 is a PCNA-binding protein that acts as a regulator of DNA repair during DNA replication. Following DNA damage, the interaction with PCNA is disrupted, facilitating the interaction between monoubiquitinated PCNA and the translesion DNA synthesis DNA polymerase eta (POLH) at stalled replisomes, facilitating the bypass of replication-fork-blocking lesions. This protein also acts as a regulator of centrosome number. Recombinant human KIAA0101 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
PCNA clamp associated factor, PAF15, PAF, p15(PAF), OEATC-1, OEATC, NS5ATP9, L5, KIAA0101
Concentration :
0.5mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Kais Z., et al (2011). Mol. Cancer Res. 9:1091-1099;; Povlsen L.K., et al (2012). Nat. Cell Biol. 14:1089-1098
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Metabolism
Molecular Weight :
14.4 kDa (134aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MVRTKAD SVPGTYRKVV AARAPRKVLG SSTSATNSTS VSSRKAENKY AGGNPVCVRP TPKWQKGIGE FFRLSPKDSE KENQIPEEAG SSGLGKAKRK ACPLQPDHTN DEKE
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
Q15004
Internal Search Terms :
PCNA clamp associated factor, PAF-15, PAF15, PAF 15, PAF, p15-PAF, p15PAF, p15/PAF, p15(PAF), p15 PAF, OEATC-1, OEATC1, OEATC, NS5ATP9, L5, KIAA0101, ATGP2304-10ug, ATGP2304-20ug, ATGP2304-50ug, ATGP2304-100ug, ATGP2304-250ug, ATGP2304-500ug, ATGP2304-1mg, ATGP2304-010, ATGP2304-020, ATGP2304-050, ATGP2304-100, ATGP2304-250, ATGP2304-500, ATGP2304-01M
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.