product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human ASCC1 protein
catalog :
ATGP2303
quantity :
10 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human ASCC1 protein
Domain :
1-357aa
Catalog number (SKU) :
ATGP2303
NCBI :
NP_001185727
Description :
ASCC1 is a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in ASCC1 are associated with Barrett esophagus and esophageal adenocarcinoma. Recombinant human ASCC1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
Activating signal cointegrator 1 complex subunit 1, ASC1p50, CGI-18, p50
Concentration :
0.5mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Almeida-Vega S., et al (2009). Am. J. Physiol. 296:G414-G423;; Orloff M., et al (2011). JAMA 306:410-419
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Signal Transduction
Molecular Weight :
43.6 kDa (380aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MGSSHHHHHH SSGLVPRGSH MGSMEVLRPQ LIRIDGRNYR KNPVQEQTYQ HEEDEEDFYQ GSMECADEPC DAYEVEQTPQ GFRSTLRAPS LLYKHIVGKR GDTRKKIEME TKTSISIPKP GQDGEIVITG QHRNGVISAR TRIDVLLDTF RRKQPFTHFL AFFLNEVEVQ EGFLRFQEEV LAKCSMDHGV DSSIFQNPKK LHLTIGMLVL LSEEEIQQTC EMLQQCKEEF INDISGGKPL EVEMAGIEYM NDDPGMVDVL YAKVHMKDGS NRLQELVDRV LERFQASGLI VKEWNSVKLH ATVMNTLFRK DPNAEGRYNL YTAEGKYIFK ERESFDGRNI LKLFENFYFG SLKLNSIHIS QRFTVDSFGN YASCGQIDFS
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
Q8N9N2
Internal Search Terms :
ASCC1, Activating signal cointegrator 1 complex subunit 1, ASC1p50, CGI-18, p50,ATGP2303-10ug,ATGP2303-20ug,ATGP2303-50ug,ATGP2303-100ug,ATGP2303-250ug,ATGP2303-500ug,ATGP2303-1mg,ATGP2303-10,ATGP2303-20,ATGP2303-50,ATGP2303-100,ATGP2303-250,ATGP2303-500,ATGP2303-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.