product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human NEURL2 protein
catalog :
ATGP2297
quantity :
10 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human NEURL2 protein
Domain :
1-285aa
Catalog number (SKU) :
ATGP2297
NCBI :
NP_542787
Description :
NEuRL2 plays an important role in the process of myofiber differentiation and maturation. This protein is probable substrate-recognition component of a SCF-like ECS (Elongin BC-CuL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of proteins. It probably contributes to catalysis through recognition and positioning of the substrate and the ubiquitin-conjugating enzyme. During myogenesis, NEuRL2 controls the ubiquitination and degradation of the specific pool of CTNNB1/beta-catenin located at the sarcolemma. Recombinant human NEuRL2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
Neuralized homolog 2, C20orf163, OZZ, Ozz-E3, Neuralized E3 ubiquitin protein ligase 2, Neuralized-like 2
Concentration :
0.5mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M UREA, 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Aurino,S., et al. (2008) Acta Myol 27, 90-97;; Song,R., et al. (2006) J. Biol. Chem. 281 (47), 36391-36400
Purity :
> 85% by SDS-PAGE
Applications :
SDS-PAGE, Denatured
Antigen Species :
Human
Gene Category :
Ubiquitination
Molecular Weight :
34.1 kDa (308aa)
Amino Acid Sequence :
MAAASEP VDSGALWGLE RPEPPPTRFH RVHGANIRVD PSGTRATRVE SFAHGVCFSR EPLAPGQVFL VEIEEKELGW CGHLRLGLTA LDPASLAPVP EFSLPDLVNL GHTWVFAITR HHNRVPREGR PEAEAAAPSR PPTLLVEPYL RIEQFRIPRD RLVGRSRPGL YSHLLDQLYE LNVLPPTARR SRLGVLFCPR PDGTADMHII INGEDMGPSA RGLPAAQPLY AVVDVFASTK SVRLVQLEYG LPSLQTLCRL VIQRSMVHRL AIDGLHLPKE LKDFCKYE
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
Q9BR09
Internal Search Terms :
Neuralized homolog 2, C20orf163, OZZ, Ozz-E3, Neuralized E3 ubiquitin protein ligase 2, Neuralized-like 2, NEuRL2, Ozz E3, Neuralized like 2, ATGP2297-10ug, ATGP2297-20ug, ATGP2297-50ug, ATGP2297-100ug, ATGP2297-250ug, ATGP2297-500ug, ATGP2297-1mg, ATGP2297-010, ATGP2297-020, ATGP2297-050, ATGP2297-100, ATGP2297-250, ATGP2297-500, ATGP2297-01M
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.