Recombinant human Granzyme K protein | NKMAX ATGP2294 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Granzyme K protein

catalog :

ATGP2294

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Granzyme K protein

Domain :

27-264aa

Catalog number (SKU) :

ATGP2294

NCBI :

NP_002095.1

Description :

GZMK is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes. Recombinant human GZMK protein, fused to His-tag at N-terminus, was expressed in E. coli.

Alternative Names :

Granzyme K, GZMK, TRYP2, GZMK, PRSS, tryptase II, Fragmentin-3, Granzyme-3, NK-tryptase-2, NK-Tryp-2

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Rucevic M, Fast LD, et al. (2007). Shock. 27(5):488-93.;; Zhao T, Zhang H, et al. (2007). J Biol Chem. 282(16):12104-11.

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE, Denatured

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

28.2 kDa (261aa)

Amino Acid Sequence :

IIGGKEV SPHSRPFMAS IQYGGHHVCG GVLIDPQWVL TAAHCQYRFT KGQSPTVVLG AHSLSKNEAS KQTLEIKKFI PFSRVTSDPQ SNDIMLVKLQ TAAKLNKHVK MLHIRSKTSL RSGTKCKVTG WGATDPDSLR PSDTLREVTV TVLSRKLCNS QSYYNGDPFI TKDMVCAGDA KGQKDSCKGD SGGPLICKGV FHAIVSGGHE CGVATKPGIY TLLTKKYQTW IKSNLVPPHT N

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P49863

Internal Search Terms :

GZMK, Granzyme K, TRYP2,ATGP2294-10ug,ATGP2294-20ug,ATGP2294-50ug,ATGP2294-100ug,ATGP2294-250ug,ATGP2294-500ug,ATGP2294-1mg,ATGP2294-10,ATGP2294-20,ATGP2294-50,ATGP2294-100,ATGP2294-250,ATGP2294-500,ATGP2294-1

more info or order :

NKMAX product webpage