Recombinant human DNA polymerase delta subunit 4/POLD4 protein

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human DNA polymerase delta subunit 4/POLD4 protein

catalog :

ATGP2282

quantity :

4 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human DNA polymerase delta subunit 4/POLD4 protein

Domain :

1-107aa

Catalog number (SKU) :

ATGP2282

NCBI :

NP_066996

Description :

POLD4 is the smallest subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The protein enhances the activity of DNA polymerase delta and plays a role in fork repair and stabilization through interactions with the DNA helicase Bloom syndrome protein. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Recombinant human POLD4 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

DNA polymerase delta 4 accessory subunit, DNA polymerase delta smallest subunit p12, DNA polymerase delta subunit p12

Concentration :

0.25mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 40% glycerol, 2mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Taylor T.D., et al. (2006) Nature. 440:497-500;; Gerhard D.S., et al. (2004) Genome Res. 14:2121-2127

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Epigenomics (Transcription & Translation)

Molecular Weight :

14.8 kDa (130aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MGSMGRKRLI TDSYPVVKRR EGPAGHSKGE LAPELGEEPQ PRDEEEAELE LLRQFDLAWQ YGPCTGITRL QRWCRAKQMG LEPPPEVWQV LKTHPGDPRF QCSLWHLYPL

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q9HCU8

Internal Search Terms :

POLD4, DNA polymerase delta subunit 4, p12, POLDS,ATGP2282-10ug,ATGP2282-20ug,ATGP2282-50ug,ATGP2282-100ug,ATGP2282-250ug,ATGP2282-500ug,ATGP2282-1mg,ATGP2282-10,ATGP2282-20,ATGP2282-50,ATGP2282-100,ATGP2282-250,ATGP2282-500,ATGP2282-1

more info or order :

NKMAX product webpage