Recombinant human PPM1F protein | NKMAX ATGP2281 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human PPM1F protein

catalog :

ATGP2281

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human PPM1F protein

Domain :

1-454aa

Catalog number (SKU) :

ATGP2281

NCBI :

NP_055449

Description :

PPM1F is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. Recombinant human PPM1F protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Protein phosphatase 1F, CAMKP, CaMKPase, FEM-2, hFEM-2, POPX2

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Tan KM, Chan SL, et al. (2001). J Biol Chem. 276(47):44193-202. ;;Harvey BP, Banga SS, et al. (2004). J Biol Chem. 279(23):24889-98.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Signal Transduction

Molecular Weight :

52.2 kDa (477aa)

Amino Acid Sequence :

MSSGAPQ KSSPMASGAE ETPGFLDTLL QDFPALLNPE DPLPWKAPGT VLSQEEVEGE LAELAMGFLG SRKAPPPLAA ALAHEAVSQL LQTDLSEFRK LPREEEEEEE DDDEEEKAPV TLLDAQSLAQ SFFNRLWEVA GQWQKQVPLA ARASQRQWLV SIHAIRNTRR KMEDRHVSLP SFNQLFGLSD PVNRAYFAVF DGHGGVDAAR YAAVHVHTNA ARQPELPTDP EGALREAFRR TDQMFLRKAK RERLQSGTTG VCALIAGATL HVAWLGDSQV ILVQQGQVVK LMEPHRPERQ DEKARIEALG GFVSHMDCWR VNGTLAVSRA IGDVFQKPYV SGEADAASRA LTGSEDYLLL ACDGFFDVVP HQEVVGLVQS HLTRQQGSGL RVAEELVAAA RERGSHDNIT VMVVFLRDPQ ELLEGGNQGE GDPQAEGRRQ DLPSSLPEPE TQAPPRS

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P49593

Internal Search Terms :

PPM1F, Protein phosphatase 1F, CAMKP, CaMKPase, FEM-2, hFEM-2, POPX2,ATGP2281-10ug,ATGP2281-20ug,ATGP2281-50ug,ATGP2281-100ug,ATGP2281-250ug,ATGP2281-500ug,ATGP2281-1mg,ATGP2281-10,ATGP2281-20,ATGP2281-50,ATGP2281-100,ATGP2281-250,ATGP2281-500,ATGP2281-1

more info or order :

NKMAX product webpage