product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human Osteoactivin/GPNMB protein
catalog :
ATGP2280
quantity :
20 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human Osteoactivin/GPNMB protein
Domain :
22-474aa
Catalog number (SKU) :
ATGP2280
NCBI :
NP_002501
Description :
GPNMB is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. The protein shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. Recombinant human GPNMB protein, fused to His-tag at N-terminus, was expressed in E. coli.
Alternative Names :
Transmembrane glycoprotein NMB, Glycoprotein NMB, Glycoprotein nonmetastatic melanoma protein B, Hematopoietic growth factor inducible neurokinin-1, HGFIN
Concentration :
1mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Rose A.A., et al. (2010) PLoS ONE. 5:e12093-e12093;; Patel-Chamberlin M., et al. (2011) Kidney Int. 79:1138-1148
Purity :
> 85% by SDS-PAGE
Applications :
SDS-PAGE, Denatured
Antigen Species :
Human
Gene Category :
Cancer
Molecular Weight :
53.2 kDa (476aa)
Amino Acid Sequence :
MGSSHHHHHH SSGLVPRGSH MGSAKRFHDV LGNERPSAYM REHNQLNGWS SDENDWNEKL YPVWKRGDMR WKNSWKGGRV QAVLTSDSPA LVGSNITFAV NLIFPRCQKE DANGNIVYEK NCRNEAGLSA DPYVYNWTAW SEDSDGENGT GQSHHNVFPD GKPFPHHPGW RRWNFIYVFH TLGQYFQKLG RCSVRVSVNT ANVTLGPQLM EVTVYRRHGR AYVPIAQVKD VYVVTDQIPV FVTMFQKNDR NSSDETFLKD LPIMFDVLIH DPSHFLNYST INYKWSFGDN TGLFVSTNHT VNHTYVLNGT FSLNLTVKAA APGPCPPPPP PPRPSKPTPS LGPAGDNPLE LSRIPDENCQ INRYGHFQAT ITIVEGILEV NIIQMTDVLM PVPWPESSLI DFVVTCQGSI PTEVCTIISD PTCEITQNTV CSPVDVDEMC LLTVRRTFNG SGTYCVNLTL GDDTSLALTS TLISVP
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
Q14956
Internal Search Terms :
GPNMB, Glycoprotein (transmembrane) nmb, HGFIN, NMB,ATGP2280-10ug,ATGP2280-20ug,ATGP2280-50ug,ATGP2280-100ug,ATGP2280-250ug,ATGP2280-500ug,ATGP2280-1mg,ATGP2280-10,ATGP2280-20,ATGP2280-50,ATGP2280-100,ATGP2280-250,ATGP2280-500,ATGP2280-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.