product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human COPS6 protein
catalog :
ATGP2261
quantity :
20 ug
price :
105 USD
more info or order :
NKMAX product webpage
product information
Product Type :
Proteins
Item Name :
Recombinant human COPS6 protein
Domain :
1-327aa
Catalog number (SKU) :
ATGP2261
NCBI :
NP_006824
Description :
COPS6 is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr. Recombinant human COPS6 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Alternative Names :
COP9 signalosome complex subunit 6, CSN6, MOV34-34KD
Concentration :
0.25mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M uREA, 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Zhao,R., et al. (2011) J. Clin. Invest. 121 (3), 851-865;; Sowa,M.E., et al. (2009) Cell 138 (2), 389-403
Purity :
> 80% by SDS-PAGE
Applications :
SDS-PAGE,Denatured
Antigen Species :
Human
Gene Category :
Epigenomics (Transcription & Translation)
Molecular Weight :
38.9 kDa (347aa)
Amino Acid Sequence :
MGSSHHHHHH SSGLVPRGSH MAAAAAAAAA TNGTGGSSGM EVDAAVVPSV MACGVTGSVS VALHPLVILN ISDHWIRMRS QEGRPVQVIG ALIGKQEGRN IEVMNSFELL SHTVEEKIII DKEYYYTKEE QFKQVFKELE FLGWYTTGGP PDPSDIHVHK QVCEIIESPL FLKLNPMTKH TDLPVSVFES VIDIINGEAT MLFAELTYTL ATEEAERIGV DHVARMTATG SGENSTVAEH LIAQHSAIKM LHSRVKLILE YVKASEAGEV PFNHEILREA YALCHCLPVL STDKFKTDFY DQCNDVGLMA YLGTITKTCN TMNQFVNKFN VLYDRQGIGR RMRGLFF
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
Q7L5N1
Internal Search Terms :
COPS6, COP9 signalosome complex subunit 6, CSN6, MOV34-34KD,ATGP2261-10ug,ATGP2261-20ug,ATGP2261-50ug,ATGP2261-100ug,ATGP2261-250ug,ATGP2261-500ug,ATGP2261-1mg,ATGP2261-10,ATGP2261-20,ATGP2261-50,ATGP2261-100,ATGP2261-250,ATGP2261-500,ATGP2261-1
more info or order :
NKMAX product webpage
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.