product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human Tmp21/p23 protein
catalog :
ATGP2253
quantity :
4 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human Tmp21/p23 protein
Domain :
32-185aa
Catalog number (SKU) :
ATGP2253
NCBI :
NP_006818
Description :
TMED10 is a member of the EMP24/GP25L/p24 family and a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. Recombinant human TMED10 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
Transmembrane emp24 domain-containing protein 10, p23, P24(DELTA), S31I125, S31III125, Tmp-21-I, TMP21
Concentration :
0.25mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Chen F, Hasegawa H, et al. (2006). Nature. 440(7088):1208-12.;; Wang H, et al. (2002). J Biol Chem. 277(6):4541-50.
Purity :
> 85% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Signal Transduction
Molecular Weight :
20 kDa (177aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MGSSHHHHHH SSGLVPRGSH MGSISFHLPI NSRKCLREEI HKDLLVTGAY EISDQSGGAG GLRSHLKITD SAGHILYSKE DATKGKFAFT TEDYDMFEVC FESKGTGRIP DQLVILDMKH GVEAKNYEEI AKVEKLKPLE VELRRLEDLS ESIVNDFAYM KKREEEMRDT NESTNTR
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
P49755
Internal Search Terms :
Tmp21, p23, Transmembrane emp24 domain-containing protein 10, p23, P24(DELTA), S31I125, S31III125, Tmp-21-I, TMP21,ATGP2253-10ug,ATGP2253-20ug,ATGP2253-50ug,ATGP2253-100ug,ATGP2253-250ug,ATGP2253-500ug,ATGP2253-1mg,ATGP2253-10,ATGP2253-20,ATGP2253-50,ATGP2253-100,ATGP2253-250,ATGP2253-500,ATGP2253-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.