Recombinant human NCK2 protein | NKMAX ATGP2235 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human NCK2 protein

catalog :

ATGP2235

quantity :

10 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human NCK2 protein

Domain :

1-380aa

Catalog number (SKU) :

ATGP2235

NCBI :

NP_003572

Description :

NCK2 is a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization. Alternate transcriptiona splice variants, encoding different isoforms, have been characterized. Recombinant human NCK2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

NCK adaptor protein 2, GRB4, NCKbeta

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol, 1mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Braverman L.E., et al. (1999) J. Biol. Chem. 274:5542-5549;; Latreille M., et al. (2006) J. Biol. Chem. 281:26633-26644

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cancer

Molecular Weight :

45.3 kDa (403aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MGSMTEEVIV IAKWDYTAQQ DQELDIKKNE RLWLLDDSKT WWRVRNAANR TGYVPSNYVE RKNSLKKGSL VKNLKDTLGL GKTRRKTSAR DASPTPSTDA EYPANGSGAD RIYDLNIPAF VKFAYVAERE DELSLVKGSR VTVMEKCSDG WWRGSYNGQI GWFPSNYVLE EVDEAAAESP SFLSLRKGAS LSNGQGSRVL HVVQTLYPFS SVTEEELNFE KGETMEVIEK PENDPEWWKC KNARGQVGLV PKNYVVVLSD GPALHPAHAP QISYTGPSSS GRFAGREWYY GNVTRHQAEC ALNERGVEGD FLIRDSESSP SDFSVSLKAS GKNKHFKVQL VDNVYCIGQR RFHTMDELVE HYKKAPIFTS EHGEKLYLVR ALQ

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

O43639

Internal Search Terms :

NCK2, NCK adaptor protein 2, GRB4, NCKbeta,ATGP2235-10ug,ATGP2235-20ug,ATGP2235-50ug,ATGP2235-100ug,ATGP2235-250ug,ATGP2235-500ug,ATGP2235-1mg,ATGP2235-10,ATGP2235-20,ATGP2235-50,ATGP2235-100,ATGP2235-250,ATGP2235-500,ATGP2235-1

more info or order :

NKMAX product webpage