Recombinant human Prohibitin 2 protein | NKMAX ATGP2184 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Prohibitin 2 protein

catalog :

ATGP2184

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Prohibitin 2 protein

Domain :

1-299aa

Catalog number (SKU) :

ATGP2184

NCBI :

NP_001138303.1

Description :

PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases by similarity. This protein functions as an estrogen receptor (ER) -selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. PHB2 competes with NCOA1 for modulation of ER transcriptional activity. It is probably involved in regulating mitochondrial respiration activity and in aging. Recombinant human PHB2 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Alternative Names :

Prohibitin 2, Bap37, p22, B cell receptor associated protein 37, BAP, BCAP37, PNAS-141, REA, PHB2

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M UREA, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Kategaya,L.S., et al. (2012) PLoS ONE 7 (2), E31987;; Emerson,V., et al. (2010) J. Virol. 84 (3), 1355-1365

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE, Denatured

Antigen Species :

Human

Gene Category :

Signal Transduction

Molecular Weight :

35.7 kDa (322aa)

Amino Acid Sequence :

MAQNLKD LAGRLPAGPR GMGTALKLLL GAGAVAYGVR ESVFTVEGGH RAIFFNRIGG VQQDTILAEG LHFRIPWFQY PIIYDIRARP RKISSPTGSK DLQMVNISLR VLSRPNAQEL PSMYQRLGLD YEERVLPSIV NEVLKSVVAK FNASQLITQR AQVSLLIRRE LTERAKDFSL ILDDVAITEL SFSREYTAAV EAKQVAQQEA QRAQFLVEKA KQEQRQKIVQ AEGEAEAAKM LGEALSKNPG YIKLRKIRAA QNISKTIATS QNRIYLTADN LVLNLQDESF TRGSDSLIKG KK

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q99623

Internal Search Terms :

B cell receptor associated protein 37, BAP, BAP 37, BAP37, BCAP 37, BCAP37, p22, PHB2, PNAS 141, PNAS141, PNAS-141, Prohibitin 2, Prohibitin2, REA, ATGP2184-10ug, ATGP2184-20ug, ATGP2184-50ug, ATGP2184-100ug, ATGP2184-250ug, ATGP2184-500ug, ATGP2184-1mg, ATGP2184-010, ATGP2184-020, ATGP2184-050, ATGP2184-100, ATGP2184-250, ATGP2184-500, ATGP2184-01M

more info or order :

NKMAX product webpage