Recombinant human KLF7 protein | NKMAX ATGP2174 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human KLF7 protein

catalog :

ATGP2174

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human KLF7 protein

Domain :

1-302aa

Catalog number (SKU) :

ATGP2174

NCBI :

NP_003700

Description :

KLF7 is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants. Recombinant human KLF7 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Alternative Names :

Kruppel-like factor 7, uKLF

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Matsumoto N., et al. (1998) J. Biol. Chem. 273:28229-28237;; Kawamura Y., et al. (2006) Mol. Endocrinol. 20:844-856

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE, Denatured

Antigen Species :

Human

Gene Category :

Epigenomics (Transcription & Translation)

Molecular Weight :

35.8 kDa (325aa)

Amino Acid Sequence :

MDVLASY SIFQELQLVH DTGYFSALPS LEETWQQTCL ELERYLQTEP RRISETFGED LDCFLHASPP PCIEESFRRL DPLLLPVEAA ICEKSSAVDI LLSRDKLLSE TCLSLQPASS SLDSYTAVNQ AQLNAVTSLT PPSSPELSRH LVKTSQTLSA VDGTVTLKLV AKKAALSSVK VGGVATAAAA VTAAGAVKSG QSDSDQGGLG AEACPENKKR VHRCQFNGCR KVYTKSSHLK AHQRTHTGEK PYKCSWEGCE WRFARSDELT RHYRKHTGAK PFKCNHCDRC FSRSDHLALH MKRHI

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

O75840

Internal Search Terms :

KLF7, Kruppel-like factor 7, uKLF,ATGP2174-10ug,ATGP2174-20ug,ATGP2174-50ug,ATGP2174-100ug,ATGP2174-250ug,ATGP2174-500ug,ATGP2174-1mg,ATGP2174-10,ATGP2174-20,ATGP2174-50,ATGP2174-100,ATGP2174-250,ATGP2174-500,ATGP2174-1

more info or order :

NKMAX product webpage