Recombinant human ASPSCR1 protein | NKMAX ATGP2165 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human ASPSCR1 protein

catalog :

ATGP2165

quantity :

4 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human ASPSCR1 protein

Domain :

1-553aa

Catalog number (SKU) :

ATGP2165

NCBI :

NP_076988.1

Description :

ASPSCR1 contains a uBX domain and interacts with glucose transporter type 4 (GLuT4). This protein is a tether, which sequesters the GLuT4 in intracellular vesicles in muscle and fat cells in the absence of insulin, and redistributes the GLuT4 to the plasma membrane within minutes of insulin stimulation. Translocation t (X;17) (p11;q25) of this gene with transcription factor TFE3 gene results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas. Recombinant human ASPSCR1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Tether containing uBX domain for GLuT4 isoform 1, ASPCR1, ASPL, ASPS, RCC17, TuG, uBXD9, uBXN9

Concentration :

0.25mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Bogan JS, Hendon N, et al. (2003). Nature. 425(6959):727-33.;; Argani P, Antonescu CR, et al. (2001). Am J Pathol. 159(1):179-92.

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Signal Transduction

Molecular Weight :

62.6 kDa (576aa)

Amino Acid Sequence :

MAAPAGG GGSAVSVLAP NGRRHTVKVT PSTVLLQVLE DTCRRQDFNP CEYDLKFQRS VLDLSLQWRF ANLPNNAKLE MVPASRSREG PENMVRIALQ LDDGSRLQDS FCSGQTLWEL LSHFPQIREC LQHPGGATPV CVYTRDEVTG EAALRGTTLQ SLGLTGGSAT IRFVMKCYDP VGKTPGSLGS SASAGQAAAS APLPLESGEL SRGDLSRPED ADTSGPCCEH TQEKQSTRAP AAAPFVPFSG GGQRLGGPPG PTRPLTSSSA KLPKSLSSPG GPSKPKKSKS GQDPQQEQEQ ERERDPQQEQ ERERPVDREP VDREPVVCHP DLEERLQAWP AELPDEFFEL TVDDVRRRLA QLKSERKRLE EAPLVTKAFR EAQIKEKLER YPKVALRVLF PDRYVLQGFF RPSETVGDLR DFVRSHLGNP ELSFYLFITP PKTVLDDHTQ TLFQANLFPA ALVHLGAEEP AGVYLEPGLL EHAISPSAAD VLVARYMSRA AGSPSPLPAP DPAPKSEPAA EEGALVPPEP IPGTAQPVKR SLGKVPKWLK LPASKR

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q9BZE9

Internal Search Terms :

ASPSCR1, Tether containing uBX domain for GLuT4 isoform 1, ASPCR1, ASPL, ASPS, RCC17, TuG, uBXD9, uBXN9,ATGP2165-10ug,ATGP2165-20ug,ATGP2165-50ug,ATGP2165-100ug,ATGP2165-250ug,ATGP2165-500ug,ATGP2165-1mg,ATGP2165-10,ATGP2165-20,ATGP2165-50,ATGP2165-100,ATGP2165-250,ATGP2165-500,ATGP2165-1

more info or order :

NKMAX product webpage