product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human PSTPIP1 protein
catalog :
ATGP2158
quantity :
20 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human PSTPIP1 protein
Domain :
1-416aa
Catalog number (SKU) :
ATGP2158
NCBI :
NP_003969
Description :
PSTPIP1 binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome. Recombinant human PSTPIP1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
Proline-serine-threonine phosphatase interacting protein 1, CD2BP1, CD2BP1L, CD2BP1S, H-PIP, PAPAS, PSTPIP
Concentration :
0.5mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Shoham N.G., et al. (2003) Proc. Natl. Acad. Sci. u.S.A. 100:13501-13506;; Wise C.A., et al. (2002) Hum. Mol. Genet. 11:961-969
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Signal Transduction
Molecular Weight :
50kDa (439aa)
Amino Acid Sequence :
MGSSHHHHHH SSGLVPRGSH MGSMMPQLQF KDAFWCRDFT AHTGYEVLLQ RLLDGRKMCK DMEELLRQRA QAEERYGKEL VQIARKAGGQ TEINSLRASF DSLKQQMENV GSSHIQLALT LREELRSLEE FRERQKEQRK KYEAVMDRVQ KSKLSLYKKA MESKKTYEQK CRDADDAEQA FERISANGHQ KQVEKSQNKA RQCKDSATEA ERVYRQSIAQ LEKVRAEWEQ EHRTTCEAFQ LQEFDRLTIL RNALWVHSNQ LSMQCVKDDE LYEEVRLTLE GCSIDADIDS FIQAKSTGTE PPAPVPYQNY YDREVTPLTS SPGIQPSCGM IKRFSGLLHG SPKTTSLAAS AASTETLTPT PERNEGVYTA IAVQEIQGNP ASPAQEYRAL YDYTAQNPDE LDLSAGDILE VILEGEDGWW TVERNGQRGF VPGSYLEKL
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
O43586
Internal Search Terms :
PSTPIP1, Proline-serine-threonine phosphatase interacting protein 1, CD2BP1, CD2BP1L, CD2BP1S, H-PIP, PAPAS, PSTPIP,ATGP2158-10ug,ATGP2158-20ug,ATGP2158-50ug,ATGP2158-100ug,ATGP2158-250ug,ATGP2158-500ug,ATGP2158-1mg,ATGP2158-10,ATGP2158-20,ATGP2158-50,ATGP2158-100,ATGP2158-250,ATGP2158-500,ATGP2158-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.