Recombinant human EED protein | NKMAX ATGP2154 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human EED protein

catalog :

ATGP2154

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human EED protein

Domain :

1-441aa

Catalog number (SKU) :

ATGP2154

NCBI :

NP_003788.2

Description :

EED is a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein interacts with enhancer of zeste 2, the cytoplasmic tail of integrin beta 7, immunodeficiency virus type 1 (HIV-1) MA protein, and histone deacetylase proteins. This protein mediates repression of gene activity through histone deacetylation, and may act as a specific regulator of integrin function. Recombinant EED protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Polycomb protein EED isoform a, embryonic ectoderm development, HEED; WAIT1

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Rietzler M, Bittner M, Kolanus W, Schuster A, Holzmann B (Nov 1998). J Biol Chem 273 (42): 27459-66;; Schumacher A, Lichtarge O, Schwartz S, Magnuson T (Jan 1999). Genomics 54 (1): 79-88

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Epigenomics (Transcription & Translation)

Molecular Weight :

52.6 kDa (464aa)

Amino Acid Sequence :

MSEREVS TAPAGTDMPA AKKQKLSSDE NSNPDLSGDE NDDAVSIESG TNTERPDTPT NTPNAPGRKS WGKGKWKSKK CKYSFKCVNS LKEDHNQPLF GVQFNWHSKE GDPLVFATVG SNRVTLYECH SQGEIRLLQS YVDADADENF YTCAWTYDSN TSHPLLAVAG SRGIIRIINP ITMQCIKHYV GHGNAINELK FHPRDPNLLL SVSKDHALRL WNIQTDTLVA IFGGVEGHRD EVLSADYDLL GEKIMSCGMD HSLKLWRINS KRMMNAIKES YDYNPNKTNR PFISQKIHFP DFSTRDIHRN YVDCVRWLGD LILSKSCENA IVCWKPGKME DDIDKIKPSE SNVTILGRFD YSQCDIWYMR FSMDFWQKML ALGNQVGKLY VWDLEVEDPH KAKCTTLTHH KCGAAIRQTS FSRDSSILIA VCDDASIWRW DRLR

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

O75530

Internal Search Terms :

EED,ATGP2154-10ug,ATGP2154-20ug,ATGP2154-50ug,ATGP2154-100ug,ATGP2154-250ug,ATGP2154-500ug,ATGP2154-1mg,ATGP2154-10,ATGP2154-20,ATGP2154-50,ATGP2154-100,ATGP2154-250,ATGP2154-500,ATGP2154-1

more info or order :

NKMAX product webpage