Recombinant human Keratin 8/KRT8 protein | NKMAX ATGP2076 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Keratin 8/KRT8 protein

catalog :

ATGP2076

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Keratin 8/KRT8 protein

Domain :

1-483aa

Catalog number (SKU) :

ATGP2076

NCBI :

NP_002264.1

Description :

KRT8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. KRT8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Recombinant human KRT8 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Alternative Names :

KO, Keratin type II cytoskeletal 8, Keratin 8, K8, K2C8, CYK8, CK8, CARD2

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Babichenko II, Grigor'ian AS et al. Arkh Patol. 2011 Nov-Dec;;73(6):18-21.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE, Denatured

Antigen Species :

Human

Gene Category :

Cytoskeleton

Molecular Weight :

56.1 kDa (506aa)

Amino Acid Sequence :

MSIRVTQ KSYKVSTSGP RAFSSRSYTS GPGSRISSSS FSRVGSSNFR GGLGGGYGGA SGMGGITAVT VNQSLLSPLV LEVDPNIQAV RTQEKEQIKT LNNKFASFID KVRFLEQQNK MLETKWSLLQ QQKTARSNMD NMFESYINNL RRQLETLGQE KLKLEAELGN MQGLVEDFKN KYEDEINKRT EMENEFVLIK KDVDEAYMNK VELESRLEGL TDEINFLRQL YEEEIRELQS QISDTSVVLS MDNSRSLDMD SIIAEVKAQY EDIANRSRAE AESMYQIKYE ELQSLAGKHG DDLRRTKTEI SEMNRNISRL QAEIEGLKGQ RASLEAAIAD AEQRGELAIK DANAKLSELE AALQRAKQDM ARQLREYQEL MNVKLALDIE IATYRKLLEG EESRLESGMQ NMSIHTKTTS GYAGGLSSAY GGLTSPGLSY SLGSSFGSGA GSSSFSRTSS SRAVVVKKIE TRDGKLVSES SDVLPK

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P05787

Internal Search Terms :

Type II cytoskeletal 8, KO, Keratin8, Keratin type II cytoskeletal 8, Keratin 8, Keratin, K-8, K8, K2C-8, K2C8, K2C 8, K 8, Cytokeratin8, Cytokeratin 8, CYK8, CYK 8, CK-8, CK8, CK 8, CARD-2, CARD2, CARD 2, ATGP2076-10ug, ATGP2076-20ug, ATGP2076-50ug, ATGP2076-100ug, ATGP2076-250ug, ATGP2076-500ug, ATGP2076-1mg, ATGP2076-010, ATGP2076-020, ATGP2076-050, ATGP2076-100, ATGP2076-250, ATGP2076-500, ATGP2076-01M

more info or order :

NKMAX product webpage