Recombinant human SPA17 protein | NKMAX ATGP2045 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human SPA17 protein

catalog :

ATGP2045

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human SPA17 protein

Domain :

1-151aa

Catalog number (SKU) :

ATGP2045

NCBI :

NP_059121

Description :

SPA17 is a protein present at the cell surface. The N-terminus has sequence similarity to human cAMP-dependent protein kinase A (PKA) type II alpha regulatory subunit (RIIa) while the C-terminus has an IQ calmodulin-binding motif. The central portion of the protein has carbohydrate binding motifs and likely functions in cell-cell adhesion. The protein was initially characterized by its involvement in the binding of sperm to the zona pellucida of the oocyte. Recent studies indicate that it is also involved in additional cell-cell adhesion functions such as immune cell migration and metastasis. Recombinant human SPA17 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Sperm surface protein Sp17, CT22, SP17, SP17-1

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Buchli R., et al. (2002) Biochim. Biophys. Acta. 1578:29-42;; Li Z., et al. (2007) Int. J. Cancer. 121:1507-1511;;

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cancer

Molecular Weight :

19.8 kDa (174aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MGSMSIPFSN THYRIPQGFG NLLEGLTREI LREQPDNIPA FAAAYFESLL EKREKTNFDP AEWGSKVEDR FYNNHAFEEQ EPPEKSDPKQ EESQISGKEE ETSVTILDSS EEDKEKEEVA AVKIQAAFRG HIAREEAKKM KTNSLQNEEK EENK

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q15506

Internal Search Terms :

SPA17, Sperm surface protein Sp17, CT22, SP17, SP17-1,ATGP2045-10ug,ATGP2045-20ug,ATGP2045-50ug,ATGP2045-100ug,ATGP2045-250ug,ATGP2045-500ug,ATGP2045-1mg,ATGP2045-10,ATGP2045-20,ATGP2045-50,ATGP2045-100,ATGP2045-250,ATGP2045-500,ATGP2045-1

more info or order :

NKMAX product webpage