product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human Cystatin C protein
catalog :
ATGP2040
quantity :
10 ug
price :
105 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human Cystatin C protein
Domain :
27-146aa
Catalog number (SKU) :
ATGP2040
NCBI :
NP_000090
Description :
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. CST3 is located in the cystatin locus and is the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. Recombinant human CST3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
Cystatin C, ARMD11, MGC117328, Cystatin-C
Concentration :
0.25mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 20% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Liu J. (2012) Transplant Proc. 44(5):1250-3.
Purity :
> 95% by SDS-PAGE
Bioactivity Comment Only :
The IC50 value is < 2.0nM. The inhibitory function of Cystatin 3 on protease activity of papain was measured by a fluorometric assay using Z-FR-AMC at pH 7.5 at 25C.
Applications :
Enzyme Activity,SDS-PAGE
Antigen Species :
Human
Gene Category :
Tags & Cell Markers
Molecular Weight :
15.6 kDa (141aa) confirmed by MALDI-TOF
Bioactivity Comment and Pics :
The IC50 value is < 2.0nM. The inhibitory function of Cystatin 3 on protease activity of papain was measured by a fluorometric assay using Z-FR-AMC at pH 7.5 at 25C.
Amino Acid Sequence :
MGSSHHHHHH SSGLVPRGSH MSSPGKPPRL VGGPMDASVE EEGVRRALDF AVGEYNKASN DMYHSRALQV VRARKQIVAG VNYFLDVELG RTTCTKTQPN LDNCPFHDQP HLKRKAFCSF QIYAVPWQGT MTLSKSTCQD A
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
P01034
Internal Search Terms :
Cystatin C, Cystatin C, ARMD11, MGC117328, Cystatin-C,ATGP2040-10ug,ATGP2040-20ug,ATGP2040-50ug,ATGP2040-100ug,ATGP2040-250ug,ATGP2040-500ug,ATGP2040-1mg,ATGP2040-10,ATGP2040-20,ATGP2040-50,ATGP2040-100,ATGP2040-250,ATGP2040-500,ATGP2040-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.