Recombinant human CD46 protein | NKMAX ATGP2036 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human CD46 protein

catalog :

ATGP2036

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human CD46 protein

Domain :

35-313aa

Catalog number (SKU) :

ATGP2036

NCBI :

NP_758860.1

Description :

Membrane cofactor protein isoform 14, also known as CD46, is a type I membrane protein that has cofactor activity for inactivation of complement components C3b and C4b by serum factor I. This function resides in the complement control protein repeats (CCPs), with CCP1-4 essential for regulation. CD46 is widely distributed on thymocytes, T cells, B cells, monocytes, granulocytes, NK cells, platelets, endothelial cells, epithelial cells, fibroblasts, placenta and sperm, but not on erythrocyte. Recombinant human CD46 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Membrane cofactor protein isoform 14, AHuS2, MCP, MIC10, TLX, TRA2.10

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 20% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Riley R C., et al. (2002) Mol Reprod Dev. 62:534-546.;; Iwata K., et al. (1995) J Biol Chem. 270:15148-15152.;;

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

33.8 kDa (302aa) confirmed by MALDI-TOF

Amino Acid Sequence :

CEEPPTF EAMELIGKPK PYYEIGERVD YKCKKGYFYI PPLATHTICD RNHTWLPVSD DACYRETCPY IRDPLNGQAV PANGTYEFGY QMHFICNEGY YLIGEEILYC ELKGSVAIWS GKPPICEKVL CTPPPKIKNG KHTFSEVEVF EYLDAVTYSC DPAPGPDPFS LIGESTIYCG DNSVWSRAAP ECKVVKCRFP VVENGKQISG FGKKFYYKAT VMFECDKGFY LDGSDTIVCD SNSTWDPPVP KCLKGPRPTY KPPVSNYPGY PKPEEGILDS LD

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P15529

Internal Search Terms :

CD46, Membrane cofactor protein isoform 14, AHuS2, MCP, MIC10, TLX, TRA2.10,ATGP2036-10ug,ATGP2036-20ug,ATGP2036-50ug,ATGP2036-100ug,ATGP2036-250ug,ATGP2036-500ug,ATGP2036-1mg,ATGP2036-10,ATGP2036-20,ATGP2036-50,ATGP2036-100,ATGP2036-250,ATGP2036-500,ATGP2036-1

more info or order :

NKMAX product webpage