Recombinant human Serpin G1/SERPING1 protein | NKMAX ATGP2014 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Serpin G1/SERPING1 protein

catalog :

ATGP2014

quantity :

20 ug

price :

105 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Serpin G1/SERPING1 protein

Domain :

23-500aa

Catalog number (SKU) :

ATGP2014

NCBI :

NP_001027466

Description :

Plasma protease C1 inhibitor, also known as SERPING1, is a member of the serpin superfamily of serine protease inhibitors. SERPING1 regulates the activation of complement factor C1 as well as the activity of activated C1 by coupling with the active catalytic site at the light chains of C1r and C1s. Therefore, it plays an important role in regulating activation of both the complement and contact systems. SERPING1 deficiency results in hereditary angioedema, which is characterized by recurrent episodes of localized angioedema of the skin, gastrointestinal mucosa or upper respiratory mucosa. Recombinant human SERPING1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Alternative Names :

Serpin family G member 1, C1NH, C1 Inh, C1 esterase inhibitor, C1-inhibiting factor, HAE1, HAE2, Plasma protease C1 inhibitor, C1-inhibitor

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Davis A E., et al. (1993) Methods Enzymol. 223:97.;; Davis A E., et al. (2004) Drog News Perspect. 17:439.;;

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE, Denatured

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

55.1 kDa (499aa)

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MNPNATSSSS QDPESLQDRG EGKVATTVIS KMLFVEPILE VSSLPTTNST TNSATKITAN TTDEPTTQPT TEPTTQPTIQ PTQPTTQLPT DSPTQPTTGS FCPGPVTLCS DLESHSTEAV LGDALVDFSL KLYHAFSAMK KVETNMAFSP FSIASLLTQV LLGAGENTKT NLESILSYPK DFTCVHQALK GFTTKGVTSV SQIFHSPDLA IRDTFVNASR TLYSSSPRVL SNNSDANLEL INTWVAKNTN NKISRLLDSL PSDTRLVLLN AIYLSAKWKT TFDPKKTRME PFHFKNSVIK VPMMNSKKYP VAHFIDQTLK AKVGQLQLSH NLSLVILVPQ NLKHRLEDME QALSPSVFKA IMEKLEMSKF QPTLLTLPRI KVTTSQDMLS IMEKLEFFDF SYDLNLCGLT EDPDLQVSAM QHQTVLELTE TGVEAAAASA ISVARTLLVF EVQQPFLFVL WDQQHKFPVF MGRVYDPRA

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P05155

Internal Search Terms :

SERPING1, SERPING 1, Serpin family G member 1, Plasma protease C1 inhibitor, HAE2, HAE1, HAE 2, HAE 1, C1NH, C1-inhibitor, C1-inhibiting factor, C1Inh, C1IN, C1 NH, C1 inhibitor, C1 inhibiting factor, C1 Inh, C1 esterase inhibitor, ATGP2014-10ug, ATGP2014-20ug, ATGP2014-50ug, ATGP2014-100ug, ATGP2014-250ug, ATGP2014-500ug, ATGP2014-1mg, ATGP2014-010, ATGP2014-020, ATGP2014-050, ATGP2014-100, ATGP2014-250, ATGP2014-500, ATGP2014-01M

more info or order :

NKMAX product webpage