Recombinant human GULP1/CED-6 protein | NKMAX ATGP2009 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human GULP1/CED-6 protein

catalog :

ATGP2009

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human GULP1/CED-6 protein

Domain :

1-304aa

Catalog number (SKU) :

ATGP2009

NCBI :

NP_057399

Description :

PTB domain-containing engulfment adapter protein 1, also known as GuLP1, is an evolutionarily conserved adaptor protein required for efficient engulfment of apoptotic cells by phagocytes. GuLP1 also helps modulate cellular glycosphingolipid and cholesterol transport. It also may play a role in the internalization and endosomal trafficking of various LRP1 ligands, such as PSAP. Increased cytoplasmic levels of GuLP1 are associated with increases in cellular levels of GTP-bound ARF6. Recombinant human GuLP1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

PTB domain-containing engulfment adapter protein 1, CED-6, GuLP

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 50% glycerol, 2mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Smits E., et al. (2000) Curr Biol. 9:1351-1354;; Su H P., et al. (2000) J Biol Chem. 275: 9542-9549.;;

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Signal Transduction

Molecular Weight :

36.9 kDa (327aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MGSMNRAFSR KKDKTWMHTP EALSKHFIPY NAKFLGSTEV EQPKGTEVVR DAVRKLKFAR HIKKSEGQKI PKVELQISIY GVKILEPKTK EVQHNCQLHR ISFCADDKTD KRIFTFICKD SESNKHLCYV FDSEKCAEEI TLTIGQAFDL AYRKFLESGG KDVETRKQIA GLQKRIQDLE TENMELKNKV QDLENQLRIT QVSAPPAGSM TPKSPSTDIF DMIPFSPISH QSSMPTRNGT QPPPVPSRST EIKRDLFGAE PFDPFNCGAA DFPPDIQSKL DEMQEGFKMG LTLEGTVFCL DPLDSRC

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q9UBP9

Internal Search Terms :

PTB domain-containing engulfment adapter protein 1, PTB domain containing engulfment adapter protein 1, CED-6, CED6, GuLP, GULP1, CED 6, GULP 1, GULP-1, ATGP2009-10ug, ATGP2009-20ug, ATGP2009-50ug, ATGP2009-100ug, ATGP2009-250ug, ATGP2009-500ug, ATGP2009-1mg, ATGP2009-010, ATGP2009-020, ATGP2009-050, ATGP2009-100, ATGP2009-250, ATGP2009-500, ATGP2009-01M

more info or order :

NKMAX product webpage