Recombinant human beta-III Tubulin protein | NKMAX ATGP1996 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human beta-III Tubulin protein

catalog :

ATGP1996

quantity :

10 ug

price :

105 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human beta-III Tubulin protein

Domain :

1-450aa

Catalog number (SKU) :

ATGP1996

NCBI :

NP_006077

Description :

Tubulin, beta 3 class III, also known as TuBB3, is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. TuBB3 plays a critical role in proper axon guidance and mantainance. Recombinant human TuBB3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Tubulin beta 3 class III, Tubulin, beta 3 class III, beta-4, CDCBM, CFEOM3A, TuBB4, TUBB3, FEOM3, fibrosis of extraocular muscles, congenital

Concentration :

0.25mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl,10% glycerol, 1mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Katsetos C.D., et al. (2003) J. Child Neurol. 18:851-866;; Tischfield M.A., et al. (2010) Cell. 140:74-87;;

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cytoskeleton

Molecular Weight :

52.8 kDa (473aa)

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MGSMREIVHI QAGQCGNQIG AKFWEVISDE HGIDPSGNYV GDSDLQLERI SVYYNEASSH KYVPRAILVD LEPGTMDSVR SGAFGHLFRP DNFIFGQSGA GNNWAKGHYT EGAELVDSVL DVVRKECENC DCLQGFQLTH SLGGGTGSGM GTLLISKVRE EYPDRIMNTF SVVPSPKVSD TVVEPYNATL SIHQLVENTD ETYCIDNEAL YDICFRTLKL ATPTYGDLNH LVSATMSGVT TSLRFPGQLN ADLRKLAVNM VPFPRLHFFM PGFAPLTARG SQQYRALTVP ELTQQMFDAK NMMAACDPRH GRYLTVATVF RGRMSMKEVD EQMLAIQSKN SSYFVEWIPN NVKVAVCDIP PRGLKMSSTF IGNSTAIQEL FKRISEQFTA MFRRKAFLHW YTGEGMDEME FTEAESNMND LVSEYQQYQD ATAEEEGEMY EDDEEESEAQ GPK

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q13509

Internal Search Terms :

TuBB3, Tubulin beta 3 class III, Tubulin, beta 3 class III, beta-4, CDCBM, CFEOM3A, TuBB4,ATGP1996-10ug,ATGP1996-20ug,ATGP1996-50ug,ATGP1996-100ug,ATGP1996-250ug,ATGP1996-500ug,ATGP1996-1mg,ATGP1996-10,ATGP1996-20,ATGP1996-50,ATGP1996-100,ATGP1996-250,ATGP1996-500,ATGP1996-1

References with this Product :

Shao Q, et al. Uncoupling of UNC5C with Polymerized TUBB3 in Microtubules Mediates Netrin-1 Repulsion. (J Neurosci. 2017){https://pubmed.ncbi.nlm.nih.gov/28483977/}

more info or order :

NKMAX product webpage