Recombinant human RAP2B protein | NKMAX ATGP1966 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human RAP2B protein

catalog :

ATGP1966

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human RAP2B protein

Domain :

1-183aa

Catalog number (SKU) :

ATGP1966

NCBI :

NP_002877

Description :

Ras-related protein Rap-2b, also known as RAP2B, belongs to a family of RAS-related genes. unlike normal ras proteins that have a nontransforming glutamine residue at aa 61, Rap2B has a threonine residue in that position. This change makes the intrinsic GTPase activity for Rap2B lower, thereby allowing it to exist in the activated state for a longer period of time than normal ras proteins. RAP2B is a platelet protein that is activated by thrombin and involved in platelet activation. RAP2B may be a novel candidate oncogene that plays important roles in carcinogenesis through activation of NF-kappaB pathway. Recombinant human RAP2B protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Ras-related protein Rap-2b, RAP2B, Member of RAS oncogene family, Small GTP binding protein, Ras family small GTP binding protein RAP2B

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Culine S., et al. (1989) Int J Cancer. 44:990-994;; Beranger F., et al. (1991) Oncogene. 6: 1835-1842.;;

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Signal Transduction

Molecular Weight :

22.9 kDa (206aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MGSMREYKVV VLGSGGVGKS ALTVQFVTGS FIEKYDPTIE DFYRKEIEVD SSPSVLEILD TAGTEQFASM RDLYIKNGQG FILVYSLVNQ QSFQDIKPMR DQIIRVKRYE RVPMILVGNK VDLEGEREVS YGEGKALAEE WSCPFMETSA KNKASVDELF AEIVRQMNYA AQPNGDEGCC SACVIL

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P61225

Internal Search Terms :

Small GTP binding protein, Ras-related protein Rap-2b, Ras-related protein RAP2B, Ras related protein RAP2B, Ras related protein Rap 2b, Ras family small GTP binding protein RAP2B, RAP2B, P61225, Member of RAS oncogene family, ATGP1966-10ug, ATGP1966-20ug, ATGP1966-50ug, ATGP1966-100ug, ATGP1966-250ug, ATGP1966-500ug, ATGP1966-1mg, ATGP1966-010, ATGP1966-020, ATGP1966-050, ATGP1966-100, ATGP1966-250, ATGP1966-500, ATGP1966-01M

more info or order :

NKMAX product webpage