Recombinant human CTLA4 protein | NKMAX ATGP1959 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human CTLA4 protein

catalog :

ATGP1959

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human CTLA4 protein

Domain :

36-161aa

Catalog number (SKU) :

ATGP1959

NCBI :

NP_005205.2

Description :

CTLA4 is a member of the immunoglobulin superfamily and transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. Recombinant human CTLA4 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Alternative Names :

Cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM precursor, Cytotoxic T-lymphocyte-associated antigen 4, CTLA-4, CD152, CELIAC3, Celiac disease 3, Insulin-dependent diabetes mellitus 12, IDDM12, CD, GSE

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Rudd CE, Taylor A, et al. (2009). Immunol Rev. 229(1):12-26.;; Stamper CC, Zhang Y, et al. (2001). Nature. 410(6828):608-11.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE, Denatured

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

15.9 kDa (149aa)

Amino Acid Sequence :

KAMHVAQ PAVVLASSRG IASFVCEYAS PGKATEVRVT VLRQADSQVT EVCAATYMMG NELTFLDDSI CTGTSSGNQV NLTIQGLRAM DTGLYICKVE LMYPPPYYLG IGNGTQIYVI DPEPCPDSD

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P16410

Internal Search Terms :

CTLA4, Cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM precursor, Cytotoxic T-lymphocyte protein 4 isoform CTLA4-TM precursor, CD, CD152, CELIAC3, GRD4, GSE, ICOS, IDDM12,ATGP1959-10ug,ATGP1959-20ug,ATGP1959-50ug,ATGP1959-100ug,ATGP1959-250ug,ATGP1959-500ug,ATGP1959-1mg,ATGP1959-10,ATGP1959-20,ATGP1959-50,ATGP1959-100,ATGP1959-250,ATGP1959-500,ATGP1959-1

more info or order :

NKMAX product webpage