product summary
Loading...
company name :
NKMAX
product type :
protein
product name :
Recombinant human DEDD protein
catalog :
ATGP1945
quantity :
10 ug
price :
105 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human DEDD protein
Domain :
1-318aa
Catalog number (SKU) :
ATGP1945
NCBI :
NP_127491
Description :
Death effector domain-containing protein, also known as DEDD, is a cytoplasmic protein. It translocates to the nucleus during CD95-mediated apoptosis, where it localizes to nucleoli-like structures, activates caspase-6 and specifically inhibits RNA polymerase I-dependent transcription. The cell death activity of DEDD relates to its nuclear localization. DEDD is widely expressed in a variety of tissues, with highest levels in the testis. Overexpression of this gene was shown to induce weak apoptosis. Recombinant human DEDD protein, fused to His-tag at N-terminus, was expressed in E. coli.
Alternative Names :
Death effector domain-containing protein, CASP8IP1, DEDD1, DEFT, FLDED1, KE05
Concentration :
0.5mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Stegh A H., et al. (1998) EMBO J. 17:5974-5986.;; Schickling O., et al. (2001) Cell Death Differ. 8:1157-1168.
Purity :
> 85% by SDS-PAGE
Applications :
SDS-PAGE, Denatured
Antigen Species :
Human
Gene Category :
Apoptosis
Molecular Weight :
38.9 kDa (338aa)
Amino Acid Sequence :
MAGLKRRASQ VWPEEHGEQE HGLYSLHRMF DIVGTHLTHR DVRVLSFLFV DVIDDHERGL IRNGRDFLLA LERQGRCDES NFRQVLQLLR IITRHDLLPY VTLKRRRAVC PDLVDKYLEE TSIRYVTPRA LSDPEPRPPQ PSKTVPPHYP VVCCPTSGPQ MCSKRPARGR ATLGSQRKRR KSVTPDPKEK QTCDIRLRVR AEYCQHETAL QGNVFSNKQD PLERQFERFN QANTILKSRD LGSIICDIKF SELTYLDAFW RDYINGSLLE ALKGVFITDS LKQAVGHEAI KLLVNVDEED YELGRQKLLR NLMLQALP
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
O75618
Internal Search Terms :
DEDD, Death effector domain-containing protein, CASP8IP1, DEDD1, DEFT, FLDED1, KE05,ATGP1945-10ug,ATGP1945-20ug,ATGP1945-50ug,ATGP1945-100ug,ATGP1945-250ug,ATGP1945-500ug,ATGP1945-1mg,ATGP1945-10,ATGP1945-20,ATGP1945-50,ATGP1945-100,ATGP1945-250,ATGP1945-500,ATGP1945-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.