Recombinant human Hexosaminidase A/HEXA protein | NKMAX ATGP1941 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Hexosaminidase A/HEXA protein

catalog :

ATGP1941

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Hexosaminidase A/HEXA protein

Domain :

89-529aa

Catalog number (SKU) :

ATGP1941

NCBI :

NP_000511.1

Description :

HEXA is the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I). Recombinant human HEXA protein, fused to His-tag at N-terminus, was expressed in E. coli.

Alternative Names :

beta-hexosaminidase subunit alpha, TSD, hexosaminidase A

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M uREA, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Nakano T., et al. (1988) J. Neurochem. 51:984-987

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE, Denatured

Antigen Species :

Human

Gene Category :

Neuroscience

Molecular Weight :

52.9 kDa (464aa)

Amino Acid Sequence :

TLEKNVL VVSVVTPGCN QLPTLESVEN YTLTINDDQC LLLSETVWGA LRGLETFSQL VWKSAEGTFF INKTEIEDFP RFPHRGLLLD TSRHYLPLSS ILDTLDVMAY NKLNVFHWHL VDDPSFPYES FTFPELMRKG SYNPVTHIYT AQDVKEVIEY ARLRGIRVLA EFDTPGHTLS WGPGIPGLLT PCYSGSEPSG TFGPVNPSLN NTYEFMSTFF LEVSSVFPDF YLHLGGDEVD FTCWKSNPEI QDFMRKKGFG EDFKQLESFY IQTLLDIVSS YGKGYVVWQE VFDNKVKIQP DTIIQVWRED IPVNYMKELE LVTKAGFRAL LSAPWYLNRI SYGPDWKDFY VVEPLAFEGT PEQKALVIGG EACMWGEYVD NTNLVPRLWP RAGAVAERLW SNKLTSDLTF AYERLSHFRC ELLRRGVQAQ PLNVGFCEQE FEQT

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P06865

Internal Search Terms :

Hexosaminidase A, HEXA, beta-hexosaminidase subunit alpha, TSD, hexosaminidase A,ATGP1941-10ug,ATGP1941-20ug,ATGP1941-50ug,ATGP1941-100ug,ATGP1941-250ug,ATGP1941-500ug,ATGP1941-1mg,ATGP1941-10,ATGP1941-20,ATGP1941-50,ATGP1941-100,ATGP1941-250,ATGP1941-500,ATGP1941-1

more info or order :

NKMAX product webpage