product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human IL-18BP protein
catalog :
ATGP1940
quantity :
20 ug
price :
80 USD
more info or order :
NKMAX product webpage
product information
Product Type :
Proteins
Item Name :
Recombinant human IL-18BP protein
Domain :
31-194aa
Catalog number (SKU) :
ATGP1940
NCBI :
NP_001138529
Description :
IL18BP functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Recombinant human IL18BP protein, fused to His-tag at N-terminus, was expressed in E. coli.
Alternative Names :
Interleukin-18-binding protein, IL18BPa, Interleukin-18-binding protein isoform, IL18BP, Tadekinig-alfa
Concentration :
1mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M uREA, 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Shimizu,C., et al. (2012) Mod Rheumatol 22 (1), 73-79;; Fujita,T.,et al. (2011) Diabetes Res. Clin. Pract. 92 (3), E66-E69
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE, Denatured
Antigen Species :
Human
Gene Category :
Immunology
Molecular Weight :
20 kDa (187aa)
Amino Acid Sequence :
MGSSHHHHHH SSGLVPRGSH MGSTPVSQTT TAATASVRST KDPCPSQPPV FPAAKQCPAL EVTWPEVEVP LNGTLSLSCV ACSRFPNFSI LYWLGNGSFI EHLPGRLWEG STSRERGSTG TQLCKALVLE QLTPALHSTN FSCVLVDPEQ VVQRHVVLAQ LWAGLRATLP PTQEALPSSH SSPQQQG
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
O95998
Internal Search Terms :
Interleukin-18 binding protein, Interleukin 18 binding protein, Interleukin-18-binding protein, IL18BPa, Interleukin 18 binding protein isoform, Interleukin-18-binding protein isoform, Interleukin18 binding protein isoform, IL18BP, Tadekinig-alfa, Tadekinig alfa, ATGP1940-10ug, ATGP1940-20ug, ATGP1940-50ug, ATGP1940-100ug, ATGP1940-250ug, ATGP1940-500ug, ATGP1940-1mg, ATGP1940-010, ATGP1940-020, ATGP1940-050, ATGP1940-100, ATGP1940-250, ATGP1940-500, ATGP1940-01M
more info or order :
NKMAX product webpage
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.