Recombinant human XPA protein | NKMAX ATGP1932 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human XPA protein

catalog :

ATGP1932

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human XPA protein

Domain :

1-273aa

Catalog number (SKU) :

ATGP1932

NCBI :

NP_000371

Description :

XPA, also known as DNA repair protein complementing XP-A cells, belong to the XPA family. This protein is involved in DNA excision repair. It Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. Defects in XPA are a cause of xeroderma pigmentosum complementation group A (XP-A), which is a rare human autosomal recessive disease characterized by solar sensitivity, high predisposition for developing cancers on areas exposed to sunlight and, in some cases, neurological abnormalities. Recombinant human XPA protein, fused to His-tag at N-terminus, was expressed in E. coli.

Alternative Names :

DNA repair protein complementing XP-A cells, XP1, XPAC

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Pan Y.R., et al. (2009) Cell Cycle 8:655-664;; James, et al. (2005) Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders.;;

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE, Denatured

Antigen Species :

Human

Gene Category :

Epigenomics (Transcription & Translation)

Molecular Weight :

33.8 kDa (296aa)

Amino Acid Sequence :

MAAADGA LPEAAALEQP AELPASVRAS IERKRQRALM LRQARLAARP YSATAAAATG GMANVKAAPK IIDTGGGFIL EEEEEEEQKI GKVVHQPGPV MEFDYVICEE CGKEFMDSYL MNHFDLPTCD NCRDADDKHK LITKTEAKQE YLLKDCDLEK REPPLKFIVK KNPHHSQWGD MKLYLKLQIV KRSLEVWGSQ EALEEAKEVR QENREKMKQK KFDKKVKELR RAVRSSVWKR ETIVHQHEYG PEENLEDDMY RKTCTMCGHE LTYEKM

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P23025

Internal Search Terms :

XPA, DNA repair protein complementing XP-A cells, XP1, XPAC,ATGP1932-10ug,ATGP1932-20ug,ATGP1932-50ug,ATGP1932-100ug,ATGP1932-250ug,ATGP1932-500ug,ATGP1932-1mg,ATGP1932-10,ATGP1932-20,ATGP1932-50,ATGP1932-100,ATGP1932-250,ATGP1932-500,ATGP1932-1

more info or order :

NKMAX product webpage