Recombinant human Bub3 protein | NKMAX ATGP1929 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Bub3 protein

catalog :

ATGP1929

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Bub3 protein

Domain :

1-328aa

Catalog number (SKU) :

ATGP1929

NCBI :

NP_004716

Description :

Mitotic checkpoint protein BuB3, also known as BuB3, is a conserved component of the mitotic spindle assembly complex (MCC). The encoded protein contains four WD repeat domains and has sequence similarity with the yeast BuB3 protein. BuB3 is essential for the kinetochore localization of BuB1 and BuBR1. BuB3 is involved in the essential spindle checkpoint pathway that operates during early embryogenesis. In addition, BuB3 plays a role in regulating the establishment of correct kinetochore-microtubule attachments. Recombinant human BuB3 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Alternative Names :

Mitotic checkpoint protein BuB3, BuB3L, hBuB3

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Martinez Exposito M J., et al. (1999) Proc Natl Acad Sci uSA. 96:8493-8498.;; Warren C D., et al. (2002) Mol Biol Cell. 13:3029-3041.

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE,Denatured

Antigen Species :

Human

Gene Category :

Cell Cycle

Molecular Weight :

39.5 kDa (351aa)

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MGSMTGSNEF KLNQPPEDGI SSVKFSPNTS QFLLVSSWDT SVRLYDVPAN SMRLKYQHTG AVLDCAFYDP THAWSGGLDH QLKMHDLNTD QENLVGTHDA PIRCVEYCPE VNVMVTGSWD QTVKLWDPRT PCNAGTFSQP EKVYTLSVSG DRLIVGTAGR RVLVWDLRNM GYVQQRRESS LKYQTRCIRA FPNKQGYVLS SIEGRVAVEY LDPSPEVQKK KYAFKCHRLK ENNIEQIYPV NAISFHNIHN TFATGGSDGF VNIWDPFNKK RLCQFHRYPT SIASLAFSND GTTLAIASSY MYEMDDTEHP EDGIFIRQVT DAETKPKSPC T

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

O43684

Internal Search Terms :

Bub3, Mitotic checkpoint protein BuB3, BuB3L, hBuB3,ATGP1929-10ug,ATGP1929-20ug,ATGP1929-50ug,ATGP1929-100ug,ATGP1929-250ug,ATGP1929-500ug,ATGP1929-1mg,ATGP1929-10,ATGP1929-20,ATGP1929-50,ATGP1929-100,ATGP1929-250,ATGP1929-500,ATGP1929-1

more info or order :

NKMAX product webpage