Recombinant human USP14 protein | NKMAX ATGP1921 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human USP14 protein

catalog :

ATGP1921

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human USP14 protein

Domain :

1-494aa

Catalog number (SKU) :

ATGP1921

NCBI :

NP_005142

Description :

uSP14 is a member of the ubiquitin-specific processing (uBP) family of proteases that is a deubiquitinating enzyme (DuB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Recombinant human uSP14 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

ubiquitin carboxyl-terminal hydrolase 14, TGT, ubiquitin thioesterase 14

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 20% glycerol, 1mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Shinji S, Naito Z, et al. (2009). Oncol Rep. 15(3):539-43.;; Mines MA, Goodwin JS, et al. (2009). J Biol Chem. 284(9):5742-52.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Epigenomics (Transcription & Translation)

Molecular Weight :

58.5 kDa (517aa)

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MGSMPLYSVT VKWGKEKFEG VELNTDEPPM VFKAQLFALT GVQPARQKVM VKGGTLKDDD WGNIKIKNGM TLLMMGSADA LPEEPSAKTV FVEDMTEEQL ASAMELPCGL TNLGNTCYMN ATVQCIRSVP ELKDALKRYA GALRASGEMA SAQYITAALR DLFDSMDKTS SSIPPIILLQ FLHMAFPQFA EKGEQGQYLQ QDANECWIQM MRVLQQKLEA IEDDSVKETD SSSASAATPS KKKSLIDQFF GVEFETTMKC TESEEEEVTK GKENQLQLSC FINQEVKYLF TGLKLRLQEE ITKQSPTLQR NALYIKSSKI SRLPAYLTIQ MVRFFYKEKE SVNAKVLKDV KFPLMLDMYE LCTPELQEKM VSFRSKFKDL EDKKVNQQPN TSDKKSSPQK EVKYEPFSFA DDIGSNNCGY YDLQAVLTHQ GRSSSSGHYV SWVKRKQDEW IKFDDDKVSI VTPEDILRLS GGGDWHIAYV LLYGPRRVEI MEEESEQ

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P54578

Internal Search Terms :

USP14, ubiquitin carboxyl-terminal hydrolase 14, TGT, ubiquitin thioesterase 14,ATGP1921-10ug,ATGP1921-20ug,ATGP1921-50ug,ATGP1921-100ug,ATGP1921-250ug,ATGP1921-500ug,ATGP1921-1mg,ATGP1921-10,ATGP1921-20,ATGP1921-50,ATGP1921-100,ATGP1921-250,ATGP1921-500,ATGP1921-1

more info or order :

NKMAX product webpage