product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human PYCRL/PYCR3 protein
catalog :
ATGP1906
quantity :
10 ug
price :
105 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human PYCRL/PYCR3 protein
Domain :
1-274aa
Catalog number (SKU) :
ATGP1906
NCBI :
AAH07993.1
Description :
PYCRL belongs to the pyrroline-5-carboxylate reductase family and functions as a homodecamer. It may play a critical role in proline bio-synthesis. Proline functions as a non-enzymatic antioxidant to minimize damage caused by reactive oxygen species (ROS) in microorganisms, animals and plants. In the last step of proline biosynthesis, PYCRL catalyzes the reduction of aldehyde dehydrogenase 4A1 (ALDH4A1) to proline using NAD (P) H as the cofactor. Recombinant human PYCRL protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
Pyrroline-5-carboxylate reductase 3, P5C reductase 3, P5CR 3
Concentration :
0.25mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 2mM DTT
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Nocek B., et al. (2005) J Mol Biol. 354:91-106.;; Krishnan N., et al. (2008) Free Radic Biol Med. 44: 671-681.
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Metabolism
Molecular Weight :
31 kDa (297aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MAAAEPS PRRVGFVGAG RMAGAIAQGL IRAGKVEAQH ILASAPTDRN LCHFQALGCR TTHSNQEVLQ SCLLVIFATK PHVLPAVLAE VAPVVTTEHI LVSVAAGVSL STLEELLPPN TRVLRVLPNL PCVVQEGAIV MARGRHVGSS ETNLLQHLLE ACGRCEEVPE AYVDIHTGLS GSGVAFVCAF SEALAEGAVK MGMPSSLAHR IAAQTLLGTA KMLLHEGQHP AQLRSDVCTP GGTTIYGLHA LEQGGLRAAT MSAVEAATCR AKELSRK
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
Q53H96
Internal Search Terms :
P5C reductase 3, P5C reductase3, P5CR 3, P5CR3, PYCRL, Pyrroline 5 carboxylate reductase 3, Pyrroline-5-carboxylate reductase 3, ATGP1906-10ug, ATGP1906-20ug, ATGP1906-50ug, ATGP1906-100ug, ATGP1906-250ug, ATGP1906-500ug, ATGP1906-1mg, ATGP1906-010, ATGP1906-020, ATGP1906-050, ATGP1906-100, ATGP1906-250, ATGP1906-500, ATGP1906-01M
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.