Recombinant human GALT protein | NKMAX ATGP1904 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human GALT protein

catalog :

ATGP1904

quantity :

10 ug

price :

140 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human GALT protein

Domain :

1-379aa

Catalog number (SKU) :

ATGP1904

NCBI :

NP_000146.2

Description :

GALT catalyzes the second step of the Leloir pathway of galactose metabolism, namely the conversion of uDP-glucose + galactose-1-phosphate to glucose-1-phosphate + uDP-galactose. The absence of this enzyme results in classic galactosemia in humans and can be fatal in the newborn period if lactose is not removed from the diet. The pathophysiology of galactosemia has not been clearly defined. Two transcript variants encoding different isoforms have been found for this gene. Recombinant human GALT protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques

Alternative Names :

Galactose-1-phosphate uridylyltransferase, Gal-1-P uridylyltransferase, uDP-glucose--hexose-1-phosphate uridylyltransferase

Concentration :

0.25mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.5) containing 0.2M NaCl, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Reichardt JK.(1992) Hum Mutat. (3):190-6.;; Tyfield L, Reichardt J, et al. (1999). Hum Mutat. (6):417-30.

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Metabolism

Molecular Weight :

45.9 kDa (403aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MSRSGT DPQQRQQASE ADAAAATFRA NDHQHIRYNP LQDEWVLVSA HRMKRPWQGQ VEPQLLKTVP RHDPLNPLCP GAIRANGEVN PQYDSTFLFD NDFPALQPDA PSPGPSDHPL FQAKSARGVC KVMCFHPWSD VTLPLMSVPE IRAVVDAWAS VTEELGAQYP WVQIFENKGA MMGCSNPHPH CQVWASSFLP DIAQREERSQ QAYKSQHGEP LLMEYSRQEL LRKERLVLTS EHWLVLVPFW ATWPYQTLLL PRRHVRRLPE LTPAERDDLA SIMKKLLTKY DNLFETSFPY SMGWHGAPTG SEAGANWNHW QLHAHYYPPL LRSATVRKFM VGYEMLAQAQ RDLTPEQAAE RLRALPEVHY HLGQKDRETA TIA

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P07902

Internal Search Terms :

GALT, Galactose-1-phosphate uridylyltransferase, Gal-1-P uridylyltransferase, uDP-glucose--hexose-1-phosphate uridylyltransferase,ATGP1904-10ug,ATGP1904-20ug,ATGP1904-50ug,ATGP1904-100ug,ATGP1904-250ug,ATGP1904-500ug,ATGP1904-1mg,ATGP1904-10,ATGP1904-20,ATGP1904-50,ATGP1904-100,ATGP1904-250,ATGP1904-500,ATGP1904-1

more info or order :

NKMAX product webpage