product summary
Loading...
company name :
NKMAX
product type :
protein
product name :
Recombinant human MyD88 protein
catalog :
ATGP1894
quantity :
20 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human MyD88 protein
Domain :
1-309aa
Catalog number (SKU) :
ATGP1894
NCBI :
NP_002459.2
Description :
Myeloid differentiation primary response gene 88, also known as MYD88, acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. This protein increases IL-8 transcription. It is involved in IL-18-mediated signaling pathway. MYD88 activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes. Recombinant human MYD88 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Alternative Names :
Myeloid differentiation primary response protein MyD88, MYD88D
Concentration :
0.5mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Kawai T., et al. (2004) Nat. Immunol A. 5:1061-1068;; Semaan N., et al. (2008) J. Immunol. 180:3485-3491
Purity :
> 85% by SDS-PAGE
Applications :
SDS-PAGE, Denatured
Antigen Species :
Human
Gene Category :
Signal Transduction
Molecular Weight :
38.7 kDa (345aa)
Amino Acid Sequence :
MRPD RAEAPGPPAM AAGGPGAGSA APVSSTSSLP LAALNMRVRR RLSLFLNVRT QVAADWTALA EEMDFEYLEI RQLETQADPT GRLLDAWQGR PGASVGRLLE LLTKLGRDDV LLELGPSIEE DCQKYILKQQ QEEAEKPLQV AAVDSSVPRT AELAGITTLD DPLGHMPERF DAFICYCPSD IQFVQEMIRQ LEQTNYRLKL CVSDRDVLPG TCVWSIASEL IEKRCRRMVV VVSDDYLQSK ECDFQTKFAL SLSPGAHQKR LIPIKYKAMK KEFPSILRFI TVCDYTNPCT KSWFWTRLAK ALSLP
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
Q99836
Internal Search Terms :
MyD88,ATGP1894-10ug,ATGP1894-20ug,ATGP1894-50ug,ATGP1894-100ug,ATGP1894-250ug,ATGP1894-500ug,ATGP1894-1mg,ATGP1894-10,ATGP1894-20,ATGP1894-50,ATGP1894-100,ATGP1894-250,ATGP1894-500,ATGP1894-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.