Recombinant human SLAM/CD150 protein | NKMAX ATGP1883 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human SLAM/CD150 protein

catalog :

ATGP1883

quantity :

4 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human SLAM/CD150 protein

Domain :

21-237aa

Catalog number (SKU) :

ATGP1883

NCBI :

NP_003028

Description :

SLAMF1 belongs to the immunoglobulin gene superfamily and is involved in T-cell stimulation. This protein is constitutively expressed on peripheral blood memory T cells, T-cell clones, immature thymocytes, and a proportion of B cells, and is rapidly induced on naive T cells after activation. High-affinity for self-ligand is important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11) -dependent signal transduction operates. Recombinant human SLAMF1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Alternative Names :

signaling lymphocytic activation molecule precursor, CD150, CDw150, SLAM

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M uREA, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Frecha,C., et al. (2011) J. Virol. 85 (12), 5975-5985 ;; Jordan,M.A., et al. (2011) . Immunol. 186 (7), 3953-3965;;

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE,Denatured

Antigen Species :

Human

Gene Category :

Stem Cell

Molecular Weight :

26.7 kDa (240aa)

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MGSASYGTGG RMMNCPKILR QLGSKVLLPL TYERINKSMN KSIHIVVTMA KSLENSVENK IVSLDPSEAG PPRYLGDRYK FYLENLTLGI RESRKEDEGW YLMTLEKNVS VQRFCLQLRL YEQVSTPEIK VLNKTQENGT CTLILGCTVE KGDHVAYSWS EKAGTHPLNP ANSSHLLSLT LGPQHADNIY ICTVSNPISN NSQTFSPWPG CRTDPSETKP

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q13291

Internal Search Terms :

SLAM, CD150, signaling lymphocytic activation molecule precursor, CD150, CDw150, SLAM,ATGP1883-10ug,ATGP1883-20ug,ATGP1883-50ug,ATGP1883-100ug,ATGP1883-250ug,ATGP1883-500ug,ATGP1883-1mg,ATGP1883-10,ATGP1883-20,ATGP1883-50,ATGP1883-100,ATGP1883-250,ATGP1883-500,ATGP1883-1

more info or order :

NKMAX product webpage