Recombinant human HFE protein | NKMAX ATGP1869 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human HFE protein

catalog :

ATGP1869

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human HFE protein

Domain :

23-306aa

Catalog number (SKU) :

ATGP1869

NCBI :

NP_000401.1

Description :

HFE, also known as HLA-H, belongs to the MHC class I family. This protein contains 1 Ig-like C1-type (immunoglobulin-like) domain. HFE is a membrane protein that is similar to MHC class I-type proteins and associates with beta-2 microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor (TFR) with transferrin. It binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin. Recombinant human HFE protein, fused to His-tag at N-terminus, was expressed in E. coli.

Alternative Names :

Hereditary hemochromatosis protein, HFE1, HH, HLA-H, MVCD7, TFQTL2

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Feder J.N., et al. (1998) Proc. Natl. Acad. Sci. u.S.A. 95:1472-1477;; West, A P, et al. (2000) J. Biol. Chem. (uNITED STATES) 275 (49): 38135-8.;;

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE, Denatured

Antigen Species :

Human

Gene Category :

Metabolism

Molecular Weight :

35.7 kDa (308aa)

Amino Acid Sequence :

RLLRSH SLHYLFMGAS EQDLGLSLFE ALGYVDDQLF VFYDHESRRV EPRTPWVSSR ISSQMWLQLS QSLKGWDHMF TVDFWTIMEN HNHSKESHTL QVILGCEMQE DNSTEGYWKY GYDGQDHLEF CPDTLDWRAA EPRAWPTKLE WERHKIRARQ NRAYLERDCP AQLQQLLELG RGVLDQQVPP LVKVTHHVTS SVTTLRCRAL NYYPQNITMK WLKDKQPMDA KEFEPKDVLP NGDGTYQGWI TLAVPPGEEQ RYTCQVEHPG LDQPLIVIWE PSPSGTLV

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q30201

Internal Search Terms :

HFE, Hereditary hemochromatosis protein, HFE1, HH, HLA-H, MVCD7, TFQTL2,ATGP1869-10ug,ATGP1869-20ug,ATGP1869-50ug,ATGP1869-100ug,ATGP1869-250ug,ATGP1869-500ug,ATGP1869-1mg,ATGP1869-10,ATGP1869-20,ATGP1869-50,ATGP1869-100,ATGP1869-250,ATGP1869-500,ATGP1869-1

more info or order :

NKMAX product webpage