Recombinant human CDK2AP2 protein | NKMAX ATGP1868 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human CDK2AP2 protein

catalog :

ATGP1868

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human CDK2AP2 protein

Domain :

1-126aa

Catalog number (SKU) :

ATGP1868

NCBI :

NP_005842

Description :

CDK2AP2, also known as DOC-1R and p14, belongs to the CDK2AP family. CDK2-associated protein is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. CDK2AP2 is a regulator for self-renewal of mouse embryonic stem cells (mESCs) under permissive conditions, and cell survival during differentiation of the mESCs into terminally differentiated cell types. CDK2AP2 may be involved in the regulation of self-renewal of stem cells during early embryogenesis. Recombinant human CDK2AP2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

cyclin-dependent kinase 2 associated protein 2, DOC-1R, p14

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 2mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Deshpande AM, et al. (2012) Stem Cells Dev. Jun 25.;; Shintani, et al. (2000) Mol. Cell. Biol. (uNITED STATES) 20 (17): 6300-7.;;

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cell Cycle

Molecular Weight :

15.5 kDa (149aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MGSMSYKPIA PAPSSTPGSS TPGPGTPVPT GSVPSPSGSV PGAGAPFRPL FNDFGPPSMG YVQAMKPPGA QGSQSTYTDL LSVIEEMGKE IRPTYAGSKS AMERLKRGII HARALVRECL AETERNART

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

O75956

Internal Search Terms :

CDK2AP2, cyclin-dependent kinase 2 associated protein 2, DOC-1R, p14,ATGP1868-10ug,ATGP1868-20ug,ATGP1868-50ug,ATGP1868-100ug,ATGP1868-250ug,ATGP1868-500ug,ATGP1868-1mg,ATGP1868-10,ATGP1868-20,ATGP1868-50,ATGP1868-100,ATGP1868-250,ATGP1868-500,ATGP1868-1

more info or order :

NKMAX product webpage